ČERVINKA, Pavel, Radim ŠPAČEK, Martin BYSTROŇ, Martin KVAŠŇÁK, Andrej KUPEC, Michaela ČERVINKOVÁ a Petr KALA. Optical Coherence Tomography-Guided Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Patients: A Pilot Study. Canadian Journal of Cardiology. New York: Elsevier Science Ltd., 2014, roč. 30, č. 4, s. 420-427. ISSN 0828-282X. Dostupné z: https://dx.doi.org/10.1016/j.cjca.2013.12.016.
Další formáty:   BibTeX LaTeX RIS
Základní údaje
Originální název Optical Coherence Tomography-Guided Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Patients: A Pilot Study
Autoři ČERVINKA, Pavel (203 Česká republika), Radim ŠPAČEK (203 Česká republika), Martin BYSTROŇ (203 Česká republika), Martin KVAŠŇÁK (203 Česká republika), Andrej KUPEC (203 Česká republika), Michaela ČERVINKOVÁ (203 Česká republika) a Petr KALA (203 Česká republika, garant, domácí).
Vydání Canadian Journal of Cardiology, New York, Elsevier Science Ltd. 2014, 0828-282X.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30201 Cardiac and Cardiovascular systems
Stát vydavatele Spojené státy
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 3.711
Kód RIV RIV/00216224:14110/14:00078392
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1016/j.cjca.2013.12.016
UT WoS 000333459100008
Klíčová slova anglicky INTRAVASCULAR ULTRASOUND; ATHEROSCLEROTIC PLAQUE; ARTERY-DISEASE; FIBROUS CAP; NO-REFLOW; THROMBUS; ANGIOPLASTY; TRIAL; PATHOGENESIS; MECHANISMS
Štítky EL OK
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Soňa Böhmová, učo 232884. Změněno: 16. 1. 2015 10:26.
Anotace
Background: The objective of our study was to assess whether optical coherence tomography (OCT) guidance could guide intervention to avoid balloon angioplasty and stenting during primary percutaneous coronary intervention. Methods: One hundred patients with ST-segment elevation myocardial infarction and thrombus-containing lesion were enrolled in this study. Thrombus aspiration was performed in all cases followed by an OCT study. After thrombectomy, no stent was implanted in residual significant stenosis (> 50%) if examination using OCT suggested that the occlusion was mostly thrombotic, provided that the patient was symptom-free and the Thrombolysis in Myocardial Infarction (TIMI) flow was >= 2. All patients managed only using thrombectomy underwent 1-week and 9-month angiography and OCT. Patients with significant lesion or those in whom thrombectomy failed to re-establish flow underwent standard treatment. Results: Based on the OCT information, 20 patients (20%) were treated only with aspiration even in the presence of angiographically detected "high-grade stenosis." Angiogram and OCT performed at 1 week and 9 months showed a "normal vessel" without significant stenosis in all 20 cases. There were no cases of major adverse cardiovascular event (including death, myocardial infarction, and target lesion revascularization) during the in-hospital period or at the 12-month follow-up. Conclusions: The results of our pilot study suggest that ST segment elevation myocardial infarction patients with TIMI 2/3 flow in the angiogram and without significant coronary narrowing using OCT examination (even in the presence of angiographically detected "high-grade stenosis"), in whom thrombus aspiration is performed in addition to optimal medical therapy might benefit only from thrombus aspiration without plain old balloon angioplasty/stenting during primary percutaneous coronary intervention. Validation of these preliminary data in larger randomized studies is warranted.
VytisknoutZobrazeno: 6. 5. 2024 07:30