Different Clinical Utility of Oropharyngeal Bacterial Screening
prior to Percutaneous Endoscopic Gastrostomy in Oncological and
Neurological Patients

J 2014

Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients

KROUPA, Radek, Jana JURÁNKOVÁ, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš PAVLÍK et. al.

Základní údaje

Originální název

Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients

Autoři

KROUPA, Radek (203 Česká republika, garant, domácí), Jana JURÁNKOVÁ (203 Česká republika, domácí), Milan DASTYCH (203 Česká republika, domácí), Michal ŠENKYŘÍK (203 Česká republika), Tomáš PAVLÍK (203 Česká republika, domácí), Jitka PROKEŠOVÁ (203 Česká republika, domácí), Markéta JEČMENOVÁ (203 Česká republika, domácí), Jiří DOLINA (203 Česká republika, domácí) a Aleš HEP (203 Česká republika, domácí)

Vydání

BioMed Research International, New York, Hindawi Publishing Corporation, 2014, 2314-6133

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

Biotechnologie a bionika

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.579

Kód RIV

RIV/00216224:14110/14:00078532

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1155/2014/590891

UT WoS

000344286300001

Klíčová slova anglicky

RESISTANT STAPHYLOCOCCUS-AUREUS; RANDOMIZED CONTROLLED-TRIAL; ANTIBIOTIC-PROPHYLAXIS; SITE INFECTION; RISK-FACTORS; GASTROINTESTINAL ENDOSCOPY; PERISTOMAL INFECTION; TUBE INSERTION; COMPLICATIONS; COLONIZATION

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 1. 2015 13:43, Soňa Böhmová

Anotace

V originále

Background. The aim of this study was to monitor oropharyngeal bacterial colonization in patients indicated for percutaneous endoscopic gastronomy (PEG). Methods. Oropharyngeal swabs were obtained from patients prior to PEG placement. A development of peristomal infection was evaluated. The analysis of oropharyngeal and peristomal site pathogens was done. Results. Consecutive 274 patients referred for PEG due to neurological disorder or cancer completed the study. Oropharyngeal colonization with pathogens was observed in 69%(190/274), dominantly in the neurologic subgroup of patients (P < 0.001). Peristomal infection occurred in 30 (10.9%) of patients and in 57% of them the correlation between oropharyngeal and peristomal agents was present. The presence of oropharyngeal pathogens was assessed as an important risk factor for the development of peristomal infection only in oncological patients (OR = 8.33, 95% CI: 1.66-41.76). Despite a high prevalence of pathogens in neurological patients, it did not influence the risk of peristomal infection with the exception for methicillin resistant Staphylococcus aureus (MRSA) carriers (OR 4.5, 95% CI: 1.08-18.76). Conclusion. During oropharyngeal microbial screening prior to the PEG insertion, the detection of pathogens may be a marker of the increased risk of peristomal infection in cancer patients only. In neurological patients the benefit of the screening is limited to the detection of MRSA carriers.

Citovat

KROUPA, Radek, Jana JURÁNKOVÁ, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš PAVLÍK, Jitka PROKEŠOVÁ, Markéta JEČMENOVÁ, Jiří DOLINA a Aleš HEP. Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients. BioMed Research International. New York: Hindawi Publishing Corporation, 2014, roč. 2014, "590891", s. 1-7. ISSN 2314-6133. Dostupné z: https://dx.doi.org/10.1155/2014/590891.

@article{1217590,
   author = {Kroupa, Radek and Juránková, Jana and Dastych, Milan and Šenkyřík, Michal and Pavlík, Tomáš and Prokešová, Jitka and Ječmenová, Markéta and Dolina, Jiří and Hep, Aleš},
   article_location = {New York},
   article_number = {"590891"},
   doi = {http://dx.doi.org/10.1155/2014/590891},
   keywords = {RESISTANT STAPHYLOCOCCUS-AUREUS; RANDOMIZED CONTROLLED-TRIAL; ANTIBIOTIC-PROPHYLAXIS; SITE INFECTION; RISK-FACTORS; GASTROINTESTINAL ENDOSCOPY; PERISTOMAL INFECTION; TUBE INSERTION; COMPLICATIONS; COLONIZATION},
   language = {eng},
   issn = {2314-6133},
   journal = {BioMed Research International},
   title = {Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients},
   volume = {2014},
   year = {2014}
}

TY  - JOUR
ID  - 1217590
AU  - Kroupa, Radek - Juránková, Jana - Dastych, Milan - Šenkyřík, Michal - Pavlík, Tomáš - Prokešová, Jitka - Ječmenová, Markéta - Dolina, Jiří - Hep, Aleš
PY  - 2014
TI  - Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients
JF  - BioMed Research International
VL  - 2014
IS  - "590891"
SP  - 1-7
EP  - 1-7
PB  - Hindawi Publishing Corporation
SN  - 23146133
KW  - RESISTANT STAPHYLOCOCCUS-AUREUS
KW  - RANDOMIZED CONTROLLED-TRIAL
KW  - ANTIBIOTIC-PROPHYLAXIS
KW  - SITE INFECTION
KW  - RISK-FACTORS
KW  - GASTROINTESTINAL ENDOSCOPY
KW  - PERISTOMAL INFECTION
KW  - TUBE INSERTION
KW  - COMPLICATIONS
KW  - COLONIZATION
N2  - Background. The aim of this study was to monitor oropharyngeal bacterial colonization in patients indicated for percutaneous endoscopic gastronomy (PEG). Methods. Oropharyngeal swabs were obtained from patients prior to PEG placement. A development of peristomal infection was evaluated. The analysis of oropharyngeal and peristomal site pathogens was done. Results. Consecutive 274 patients referred for PEG due to neurological disorder or cancer completed the study. Oropharyngeal colonization with pathogens was observed in 69%(190/274), dominantly in the neurologic subgroup of patients (P < 0.001). Peristomal infection occurred in 30 (10.9%) of patients and in 57% of them the correlation between oropharyngeal and peristomal agents was present. The presence of oropharyngeal pathogens was assessed as an important risk factor for the development of peristomal infection only in oncological patients (OR = 8.33, 95% CI: 1.66-41.76). Despite a high prevalence of pathogens in neurological patients, it did not influence the risk of peristomal infection with the exception for methicillin resistant Staphylococcus aureus (MRSA) carriers (OR 4.5, 95% CI: 1.08-18.76). Conclusion. During oropharyngeal microbial screening prior to the PEG insertion, the detection of pathogens may be a marker of the increased risk of peristomal infection in cancer patients only. In neurological patients the benefit of the screening is limited to the detection of MRSA carriers.
ER  -

KROUPA, Radek, Jana JURÁNKOVÁ, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš PAVLÍK, Jitka PROKEŠOVÁ, Markéta JEČMENOVÁ, Jiří DOLINA a Aleš HEP. Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients. \textit{BioMed Research International}. New York: Hindawi Publishing Corporation, 2014, roč.~2014, ''590891'', s.~1-7. ISSN~2314-6133. Dostupné z: https://dx.doi.org/10.1155/2014/590891.

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