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@article{1217605,
author = {Sachlova, Milana and Májek, Ondřej and Tuček, Štěpán},
article_location = {Abingdon},
article_number = {8},
doi = {http://dx.doi.org/10.1080/01635581.2014.956261},
keywords = {QUALITY-OF-LIFE; CELL LUNG-CANCER; WEIGHT-LOSS; SERUM-ALBUMIN; COLORECTAL-CANCER; PANCREATIC-CANCER; CARCINOEMBRYONIC ANTIGEN; GASTROESOPHAGEAL CANCER; NUTRITIONAL-STATUS; PERFORMANCE STATUS},
language = {eng},
issn = {0163-5581},
journal = {Nutrition and cancer},
title = {Prognostic Value of Scores Based on Malnutrition or Systemic Inflammatory Response in Patients With Metastatic or Recurrent Gastric Cancer},
volume = {66},
year = {2014}
}
TY - JOUR
ID - 1217605
AU - Sachlova, Milana - Májek, Ondřej - Tuček, Štěpán
PY - 2014
TI - Prognostic Value of Scores Based on Malnutrition or Systemic Inflammatory Response in Patients With Metastatic or Recurrent Gastric Cancer
JF - Nutrition and cancer
VL - 66
IS - 8
SP - 1362-1370
EP - 1362-1370
PB - Routlege journals, Taylor & Francis Ltd
SN - 01635581
KW - QUALITY-OF-LIFE
KW - CELL LUNG-CANCER
KW - WEIGHT-LOSS
KW - SERUM-ALBUMIN
KW - COLORECTAL-CANCER
KW - PANCREATIC-CANCER
KW - CARCINOEMBRYONIC ANTIGEN
KW - GASTROESOPHAGEAL CANCER
KW - NUTRITIONAL-STATUS
KW - PERFORMANCE STATUS
N2 - Cancer patients are frequently affected by malnutrition and weight loss, which affects their prognosis, length of hospital stay, health care costs, quality of life and survival. Our aim was to assess the prognostic value of different scores based on malnutrition or systemic inflammatory response in 91 metastatic or recurrent gastric cancer patients considered for palliative chemotherapy at the Masaryk Memorial Cancer Institute. We investigated their overall survival according to the following measures: Onodera's Prognostic Nutritional Index (OPNI), Glasgow Prognostic Score (GPS), nutritional risk indicator (NRI), Cancer Cachexia Study Group (CCSG), as previously defined, and a simple preadmission weight loss. The OPNI, GPS, and CCSG provided very significant prognostic values for survival (log-rank test P value < 0.001). For example, the median survival for patients with GPS 0 was 12.3 mo [95% confidence interval (CI): 7.7-16.7], whereas the median survival for patients with GPS 2 was only 2.9 mo (95% CI: 1.9-4.8). A significantly worse survival of malnourished patients was also suggested by a multivariate model. The values of GPS, OPNI, and CCSG represent useful tools for the evaluation of patients' prognosis and should be part of a routine evaluation of patients to provide a timely nutrition support.
ER -
SACHLOVA, Milana, Ondřej MÁJEK a Štěpán TUČEK. Prognostic Value of Scores Based on Malnutrition or Systemic Inflammatory Response in Patients With Metastatic or Recurrent Gastric Cancer. \textit{Nutrition and cancer}. Abingdon: Routlege journals, Taylor \&{} Francis Ltd, 2014, roč.~66, č.~8, s.~1362-1370. ISSN~0163-5581. Dostupné z: https://dx.doi.org/10.1080/01635581.2014.956261.
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