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@article{1225861,
author = {Thorenoor, Nithyananda and Slabý, Ondřej},
article_location = {Dordrecht (Netherlands)},
article_number = {1},
doi = {http://dx.doi.org/10.1007/s13277-014-2818-8},
keywords = {cancer; small nucleolar RNAs; non-coding RNAs; GAS5},
language = {eng},
issn = {1010-4283},
journal = {Tumor Biology},
title = {Small nucleolar RNAs functioning and potential roles in cancer},
url = {http://link.springer.com/article/10.1007%2Fs13277-014-2818-8},
volume = {36},
year = {2015}
}
TY - JOUR
ID - 1225861
AU - Thorenoor, Nithyananda - Slabý, Ondřej
PY - 2015
TI - Small nucleolar RNAs functioning and potential roles in cancer
JF - Tumor Biology
VL - 36
IS - 1
SP - 41-53
EP - 41-53
PB - Springer Netherlands
SN - 10104283
KW - cancer
KW - small nucleolar RNAs
KW - non-coding RNAs
KW - GAS5
UR - http://link.springer.com/article/10.1007%2Fs13277-014-2818-8
L2 - http://link.springer.com/article/10.1007%2Fs13277-014-2818-8
N2 - Non-coding RNAs (ncRNAs) are important regu- latory molecules involved in various physiological and path- ological cellular processes. Small nucleolar RNAs (snoRNAs), subclass of small ncRNAs, have been considered important but unglamorous elements in the production of protein synthesis machinery of cells. However, recent evi- dence has indicated that these non-coding RNAs might have a crucial role also in controlling cell behavior, and snoRNAs dysfunction could significantly contribute to carcinogenesis. Here, we summarize the most important aspects of snoRNAs biology, their functioning in cancer cell, and potential usage in diagnosis or as a new class of therapeutic targets in cancer.
ER -
THORENOOR, Nithyananda a Ondřej SLABÝ. Small nucleolar RNAs functioning and potential roles in cancer. \textit{Tumor Biology}. Dordrecht (Netherlands): Springer Netherlands, 2015, roč.~36, č.~1, s.~41-53. ISSN~1010-4283. Dostupné z: https://dx.doi.org/10.1007/s13277-014-2818-8.
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