2015
Small nucleolar RNAs functioning and potential roles in cancer
THORENOOR, Nithyananda and Ondřej SLABÝBasic information
Original name
Small nucleolar RNAs functioning and potential roles in cancer
Authors
THORENOOR, Nithyananda (356 India, belonging to the institution) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution)
Edition
Tumor Biology, Dordrecht (Netherlands), Springer Netherlands, 2015, 1010-4283
Other information
Language
English
Type of outcome
Article in a journal
Field of Study
30200 3.2 Clinical medicine
Country of publisher
Netherlands
Confidentiality degree
is not subject to a state or trade secret
References:
Impact factor
Impact factor: 2.926
RIV identification code
RIV/00216224:14740/15:00082370
Organization unit
Central European Institute of Technology
UT WoS
000350477300006
EID Scopus
2-s2.0-84925520015
Keywords in English
cancer; small nucleolar RNAs; non-coding RNAs; GAS5
Tags
Tags
International impact, Reviewed
Changed: 24/9/2015 15:34, Martina Prášilová
Abstract
In the original language
Non-coding RNAs (ncRNAs) are important regu- latory molecules involved in various physiological and path- ological cellular processes. Small nucleolar RNAs (snoRNAs), subclass of small ncRNAs, have been considered important but unglamorous elements in the production of protein synthesis machinery of cells. However, recent evi- dence has indicated that these non-coding RNAs might have a crucial role also in controlling cell behavior, and snoRNAs dysfunction could significantly contribute to carcinogenesis. Here, we summarize the most important aspects of snoRNAs biology, their functioning in cancer cell, and potential usage in diagnosis or as a new class of therapeutic targets in cancer.
Links
| ED1.1.00/02.0068, research and development project |
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| EE2.3.30.0037, research and development project |
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