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@article{1226570, author = {Konečný, Tomáš and Park, Jae Yoon and Somers, Kiran R. and Konecny, Dana and Orban, Marek and Souček, Filip and Parker, Kenneth O. and Scanlon, Paul D. and Asirvatham, Samuel J. and Brady, Peter A. and Rihal, Charanjit S.}, article_location = {Bridgewater}, article_number = {2}, doi = {http://dx.doi.org/10.1016/j.amjcard.2014.04.030}, keywords = {POPULATION-BASED COHORT; CHRONIC LUNG-DISEASE; CARDIOVASCULAR-DISEASE; CARDIAC-ARRHYTHMIAS; CATHETER ABLATION; RISK-FACTORS; COPD; FIBRILLATION; MORTALITY; HEALTH}, language = {eng}, issn = {0002-9149}, journal = {American Journal of Cardiology}, title = {Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias}, url = {http://www.ajconline.org/article/S0002-9149(14)01044-3/abstract}, volume = {114}, year = {2014} }
TY - JOUR ID - 1226570 AU - Konečný, Tomáš - Park, Jae Yoon - Somers, Kiran R. - Konecny, Dana - Orban, Marek - Souček, Filip - Parker, Kenneth O. - Scanlon, Paul D. - Asirvatham, Samuel J. - Brady, Peter A. - Rihal, Charanjit S. PY - 2014 TI - Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias JF - American Journal of Cardiology VL - 114 IS - 2 SP - 272-277 EP - 272-277 PB - EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC SN - 00029149 KW - POPULATION-BASED COHORT KW - CHRONIC LUNG-DISEASE KW - CARDIOVASCULAR-DISEASE KW - CARDIAC-ARRHYTHMIAS KW - CATHETER ABLATION KW - RISK-FACTORS KW - COPD KW - FIBRILLATION KW - MORTALITY KW - HEALTH UR - http://www.ajconline.org/article/S0002-9149(14)01044-3/abstract N2 - Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality, yet the exact pathophysiological links remain unclear. Whether the presence and severity of COPD are associated with atrial or ventricular arrhythmias recorded on continuous electrocardiographic monitoring is unknown. We identified consecutive adult patients who underwent clinically indicated pulmonary function testing as well as 24-hour Holter monitoring at the Mayo Clinic, Rochester, from 2000 to 2009. Demographic data and relevant co-morbidities were gathered from the electronic medical record; severity of COPD was classified according to the GOLD classification, and arrhythmias were classified in concordance with the current clinical guidelines. From 7,441 patients who were included (age 64 +/- 16 years, 49% woman, 92% Caucasian), COPD was diagnosed in 3,121 (41.9%). Compared with those without COPD, the presence and severity of COPD were associated with increased likelihood of atrial fibrillation/atrial flutter (AF/AFL; 23.3% vs 11.0%, respectively, p <0.0001), nonsustained ventricular tachycardia (NSVT; 13.0% vs 5.9%, respectively, p <0.0001), and sustained ventricular tachycardia (0.9% vs 1.6%, respectively, p <0.0001). COPD remained a significant predictor of AF/AFL and NSVT (p <0.0001 and p <0.0001, respectively) after adjusting for age, gender, tobacco use, obesity, hypertension, coronary artery disease, heart failure, diabetes, anemia, cancer, chronic kidney disease, and rate/rhythm control medications. In conclusion, the independent association between the presence and severity of COPD and arrhythmias (AF/AFL and NSVT) provides further insight into the markedly increased cardiovascular mortality of patients with COPD. Further studies should explore which anti-arrhythmic strategies would best apply to the patients with COPD. ER -
KONEČNÝ, Tomáš, Jae Yoon PARK, Kiran R. SOMERS, Dana KONECNY, Marek ORBAN, Filip SOUČEK, Kenneth O. PARKER, Paul D. SCANLON, Samuel J. ASIRVATHAM, Peter A. BRADY a Charanjit S. RIHAL. Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias. \textit{American Journal of Cardiology}. Bridgewater: EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2014, roč.~114, č.~2, s.~272-277. ISSN~0002-9149. Dostupné z: https://dx.doi.org/10.1016/j.amjcard.2014.04.030.
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