| KACEROVSKY, Marian, Ivana MUSILOVA, Bo JACOBSSON, Marcela DRAHOSOVA, Helena HORNYCHOVA, Petr JANKŮ, Martin PROCHAZKA, Ondrej SIMETKA a Ctirad ANDRYS. Vaginal fluid IL-6 and IL-8 levels in pregnancies complicated by preterm prelabor membrane ruptures. Journal of Maternal-Fetal & Neonatal Medicine. London: INFORMA HEALTHCARE, 2015, roč. 28, č. 4, s. 392-398. ISSN 1476-7058. Dostupné z: https://dx.doi.org/10.3109/14767058.2014.917625. |
Další formáty:
BibTeX
LaTeX
RIS
@article{1228682,
author = {Kacerovsky, Marian and Musilova, Ivana and Jacobsson, Bo and Drahosova, Marcela and Hornychova, Helena and Janků, Petr and Prochazka, Martin and Simetka, Ondrej and Andrys, Ctirad},
article_location = {London},
article_number = {4},
doi = {http://dx.doi.org/10.3109/14767058.2014.917625},
keywords = {histological chorioamnionitis; microbial invasion of the amniotic cavity; preterm delivery},
language = {eng},
issn = {1476-7058},
journal = {Journal of Maternal-Fetal & Neonatal Medicine},
title = {Vaginal fluid IL-6 and IL-8 levels in pregnancies complicated by preterm prelabor membrane ruptures},
volume = {28},
year = {2015}
}
TY - JOUR
ID - 1228682
AU - Kacerovsky, Marian - Musilova, Ivana - Jacobsson, Bo - Drahosova, Marcela - Hornychova, Helena - Janků, Petr - Prochazka, Martin - Simetka, Ondrej - Andrys, Ctirad
PY - 2015
TI - Vaginal fluid IL-6 and IL-8 levels in pregnancies complicated by preterm prelabor membrane ruptures
JF - Journal of Maternal-Fetal & Neonatal Medicine
VL - 28
IS - 4
SP - 392-398
EP - 392-398
PB - INFORMA HEALTHCARE
SN - 14767058
KW - histological chorioamnionitis
KW - microbial invasion of the amniotic cavity
KW - preterm delivery
N2 - Objective: To determine the vaginal fluid interleukin (IL)-6 and IL-8 concentrations in pregnancies complicated by preterm prelabor rupture of membranes and their correlation to microbial invasion of the amniotic cavity (MIAC) as well as histological chorioamnionitis (HCA). Methods: Sixty-eight women with singleton pregnancies were included in this study. Vaginal fluid was collected at the time of admission. IL-6 and IL-8 concentrations in the vaginal fluid were determined using ELISA. Result: Women with MIAC had higher vaginal fluid IL-6 levels compared to those without MIAC (with MIAC: median 374 pg/mL versus without MIAC: median 174 pg/mL; p=0.03). IL-8 levels were higher in women with MIAC only in the crude analysis but not after adjustment for gestational age. There was no difference in the IL-6 and IL-8 concentrations between those with and without HCA. Women with both MIAC and HCA had higher IL-6 vaginal fluid levels than those without both MIAC and HCA (with MIAC and HCA: median 466 pg/mL versus without MIAC and HCA: median 178 pg/mL; p=0.02). IL-8 levels were higher in women with MIAC and HCA only in the crude analysis but not after adjustment for gestational age. Conclusions: Vaginal fluid IL-6 but not IL-8 levels reflect the presence of MIAC and both MIAC and HCA.
ER -
KACEROVSKY, Marian, Ivana MUSILOVA, Bo JACOBSSON, Marcela DRAHOSOVA, Helena HORNYCHOVA, Petr JANKŮ, Martin PROCHAZKA, Ondrej SIMETKA a Ctirad ANDRYS. Vaginal fluid IL-6 and IL-8 levels in pregnancies complicated by preterm prelabor membrane ruptures. \textit{Journal of Maternal-Fetal \&{} Neonatal Medicine}. London: INFORMA HEALTHCARE, 2015, roč.~28, č.~4, s.~392-398. ISSN~1476-7058. Dostupné z: https://dx.doi.org/10.3109/14767058.2014.917625.
|
