Endocrine Disrupting Compounds Affecting Corticosteroid
Signaling Pathways in Czech and Swiss Waters: Potential Impact
on Fish

J 2014

Endocrine Disrupting Compounds Affecting Corticosteroid Signaling Pathways in Czech and Swiss Waters: Potential Impact on Fish

MACÍKOVÁ, Petra, Ksenia J. GROH, Adrian A. AMMANN, Kristin SCHIRMER, Marc J.-F. SUTER et. al.

Základní údaje

Originální název

Endocrine Disrupting Compounds Affecting Corticosteroid Signaling Pathways in Czech and Swiss Waters: Potential Impact on Fish

Autoři

MACÍKOVÁ, Petra (203 Česká republika, garant, domácí), Ksenia J. GROH (756 Švýcarsko), Adrian A. AMMANN (756 Švýcarsko), Kristin SCHIRMER (756 Švýcarsko) a Marc J.-F. SUTER (756 Švýcarsko)

Vydání

ENVIRONMENTAL SCIENCE & TECHNOLOGY, WASHINGTON, AMER CHEMICAL SOC, 2014, 0013-936X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.330

Kód RIV

RIV/00216224:14310/14:00079392

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1021/es502711c

UT WoS

000344449100051

Klíčová slova anglicky

ENVIRONMENTAL RISK-ASSESSMENT; TANDEM MASS-SPECTROMETRY; SEWAGE-TREATMENT PLANTS; ZEBRAFISH DANIO-RERIO; RAINBOW-TROUT; WASTE-WATER; GLUCOCORTICOID-RECEPTOR; GENE-EXPRESSION; ONCORHYNCHUS-MYKISS; SURFACE WATERS

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 3. 2015 09:35, Ing. Filip Vaculovič

Anotace

V originále

This study investigated the occurrence of corticosteroid signaling disruptors in wastewaters and rivers in the Czech Republic and in Switzerland. 36 target compounds were detected using HPLC-MS/MS, with up to 6.4 mu g/L for azole antifungals that indirectly affect corticosteroid signaling. Glucocorticoid receptor (GR)-mediated activity was determined using the GR-CALUX bioassay with dexamethasone equivalent concentrations ranging from

Návaznosti

LO1214, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Centrum pro výzkum toxických látek v prostředí

Citovat

MACÍKOVÁ, Petra, Ksenia J. GROH, Adrian A. AMMANN, Kristin SCHIRMER a Marc J.-F. SUTER. Endocrine Disrupting Compounds Affecting Corticosteroid Signaling Pathways in Czech and Swiss Waters: Potential Impact on Fish. ENVIRONMENTAL SCIENCE & TECHNOLOGY. WASHINGTON: AMER CHEMICAL SOC, 2014, roč. 48, č. 21, s. 12902-12911. ISSN 0013-936X. Dostupné z: https://dx.doi.org/10.1021/es502711c.

@article{1229202,
   author = {Macíková, Petra and Groh, Ksenia J. and Ammann, Adrian A. and Schirmer, Kristin and Suter, Marc J.andF.},
   article_location = {WASHINGTON},
   article_number = {21},
   doi = {http://dx.doi.org/10.1021/es502711c},
   keywords = {ENVIRONMENTAL RISK-ASSESSMENT; TANDEM MASS-SPECTROMETRY; SEWAGE-TREATMENT PLANTS; ZEBRAFISH DANIO-RERIO; RAINBOW-TROUT; WASTE-WATER; GLUCOCORTICOID-RECEPTOR; GENE-EXPRESSION; ONCORHYNCHUS-MYKISS; SURFACE WATERS},
   language = {eng},
   issn = {0013-936X},
   journal = {ENVIRONMENTAL SCIENCE & TECHNOLOGY},
   title = {Endocrine Disrupting Compounds Affecting Corticosteroid Signaling Pathways in Czech and Swiss Waters: Potential Impact on Fish},
   url = {http://pubs.acs.org/doi/abs/10.1021/es502711c},
   volume = {48},
   year = {2014}
}

TY  - JOUR
ID  - 1229202
AU  - Macíková, Petra - Groh, Ksenia J. - Ammann, Adrian A. - Schirmer, Kristin - Suter, Marc J.-F.
PY  - 2014
TI  - Endocrine Disrupting Compounds Affecting Corticosteroid Signaling Pathways in Czech and Swiss Waters: Potential Impact on Fish
JF  - ENVIRONMENTAL SCIENCE & TECHNOLOGY
VL  - 48
IS  - 21
SP  - 12902-12911
EP  - 12902-12911
PB  - AMER CHEMICAL SOC
SN  - 0013936X
KW  - ENVIRONMENTAL RISK-ASSESSMENT
KW  - TANDEM MASS-SPECTROMETRY
KW  - SEWAGE-TREATMENT PLANTS
KW  - ZEBRAFISH DANIO-RERIO
KW  - RAINBOW-TROUT
KW  - WASTE-WATER
KW  - GLUCOCORTICOID-RECEPTOR
KW  - GENE-EXPRESSION
KW  - ONCORHYNCHUS-MYKISS
KW  - SURFACE WATERS
UR  - http://pubs.acs.org/doi/abs/10.1021/es502711c
L2  - http://pubs.acs.org/doi/abs/10.1021/es502711c
N2  - This study investigated the occurrence of corticosteroid signaling disruptors in wastewaters and rivers in the Czech Republic and in Switzerland. 36 target compounds were detected using HPLC-MS/MS, with up to 6.4 mu g/L for azole antifungals that indirectly affect corticosteroid signaling. Glucocorticoid receptor (GR)-mediated activity was determined using the GR-CALUX bioassay with dexamethasone equivalent concentrations ranging from
ER  -

MACÍKOVÁ, Petra, Ksenia J. GROH, Adrian A. AMMANN, Kristin SCHIRMER a Marc J.-F. SUTER. Endocrine Disrupting Compounds Affecting Corticosteroid Signaling Pathways in Czech and Swiss Waters: Potential Impact on Fish. \textit{ENVIRONMENTAL SCIENCE \&{}amp; TECHNOLOGY}. WASHINGTON: AMER CHEMICAL SOC, 2014, roč.~48, č.~21, s.~12902-12911. ISSN~0013-936X. Dostupné z: https://dx.doi.org/10.1021/es502711c.

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