| STÁREK, Zdeněk, František LEHAR, Jiří JEŽ, Jiří WOLF and Miroslav NOVÁK. Hybrid therapy in the management of atrial fibrillation. Current Cardiology Reviews. San Francisco: Bentham Science Publishers B.V., 2015, vol. 11, No 2, p. 167-179. ISSN 1573-403X. Available from: https://dx.doi.org/10.2174/1573403X10666140713172231. |
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@article{1229900,
author = {Stárek, Zdeněk and Lehar, František and Jež, Jiří and Wolf, Jiří and Novák, Miroslav},
article_location = {San Francisco},
article_number = {2},
doi = {http://dx.doi.org/10.2174/1573403X10666140713172231},
keywords = {Atrial fibrillation; catheter ablation of arrhythmias; pharmacological antiarrhythmic therapy; hybrid therapy},
language = {eng},
issn = {1573-403X},
journal = {Current Cardiology Reviews},
title = {Hybrid therapy in the management of atrial fibrillation},
volume = {11},
year = {2015}
}
TY - JOUR
ID - 1229900
AU - Stárek, Zdeněk - Lehar, František - Jež, Jiří - Wolf, Jiří - Novák, Miroslav
PY - 2015
TI - Hybrid therapy in the management of atrial fibrillation
JF - Current Cardiology Reviews
VL - 11
IS - 2
SP - 167-179
EP - 167-179
PB - Bentham Science Publishers B.V.
SN - 1573403X
KW - Atrial fibrillation
KW - catheter ablation of arrhythmias
KW - pharmacological antiarrhythmic therapy
KW - hybrid therapy
N2 - Atrial fibrillation is the most common sustained arrhythmia. Because of the sub-optimal outcomes and associated risks of medical therapy as well as the recent advances in non-pharmacologic strategies, a multitude of combined (hybrid) algorithms have been introduced that improve efficacy of standalone therapies while maintaining a high safety profile. Antiarrhythmic administration enhances success rate of electrical cardioversion. Catheter ablation of antiarrhythmic drug-induced typical atrial flutter may prevent recurrent atrial fibrillation. Through simple ablation in the right atrium, suppression of atrial fibrillation may be achieved in patients with previously ineffective antiarrhythmic therapy. Efficacy of complex catheter ablation in the left atrium is improved with antiarrhythmic drugs. Catheter ablation followed by permanent pacemaker implantation is an effective and safe treatment option for selected patients. Additional strategies include pacing therapies such as atrial pacing with permanent pacemakers, preventive pacing algorithms, and/or implantable dual-chamber defibrillators are available. Modern hybrid strategies combining both epicardial and endocardial approaches in order to create a complex set of radiofrequency lesions in the left atrium have demonstrated a high rate of success and warrant further research. Hybrid therapy for atrial fibrillation reviews history of development of non-pharmacological treatment strategies and outlines avenues of ongoing research in this field.
ER -
STÁREK, Zdeněk, František LEHAR, Jiří JEŽ, Jiří WOLF and Miroslav NOVÁK. Hybrid therapy in the management of atrial fibrillation. \textit{Current Cardiology Reviews}. San Francisco: Bentham Science Publishers B.V., 2015, vol.~11, No~2, p.~167-179. ISSN~1573-403X. Available from: https://dx.doi.org/10.2174/1573403X10666140713172231.
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