Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two
generations of Daphnia magna

J 2015

Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna

BONA, Mirco Dalla, Radka ZOUNKOVÁ, Roberta MERLANTI, Luděk BLÁHA, Marco DE LIGUORO et. al.

Základní údaje

Originální název

Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna

Autoři

BONA, Mirco Dalla (380 Itálie, garant), Radka ZOUNKOVÁ (203 Česká republika, domácí), Roberta MERLANTI (380 Itálie), Luděk BLÁHA (203 Česká republika, domácí) a Marco DE LIGUORO (380 Itálie)

Vydání

Ecotoxicology and Environmental Safety, SAN DIEGO (USA), Academic Press, 2015, 0147-6513

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30304 Public and environmental health

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.130

Kód RIV

RIV/00216224:14310/15:00082517

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.ecoenv.2014.11.018

UT WoS

000348966400020

Klíčová slova anglicky

Daphnia magna; Fluoroquinolones; Trimethoprim; Transgenerational toxicity

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 6. 4. 2016 09:55, Ing. Andrea Mikešková

Anotace

V originále

Multigenerational tests on Daphnia magna were performed exposing two subsequent generation to enrofloxacin (EFX) and its metabolite ciprofloxacin (CPX), and to trimethoprim (TMP). Mortality rate of 100% and 50% was detected in F0 at concentrations of >= 13 mg L-1 (EFX) and 50 mg L-1 (TMP), respectively. In F1 with respect to FO, both for growth and reproduction, a worsening trend of the response with EFX, a similar response with CPX and an attenuating trend with TMP was observed. Furthermore, the lowest EC20 for reproduction inhibition (1.3 mg L-1) was calculated for F1 exposed to EFX. However, other experimentations, longer and more complex, are necessary in order to confirm that EFX is more hazardous to daphnids than CPX and TMP. EC50 measured for the three assayed antibacterials were in the 6.5-37 mg L-1 range therefore environmental unrealistic, except in case of exceptional contaminations that may occur in relation to poorly controlled wastewaters from pharmaceutical factories or excessive use of prophylactic treatments in aquaculture.

Návaznosti

LO1214, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Centrum pro výzkum toxických látek v prostředí

Citovat

BONA, Mirco Dalla, Radka ZOUNKOVÁ, Roberta MERLANTI, Luděk BLÁHA a Marco DE LIGUORO. Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna. Ecotoxicology and Environmental Safety. SAN DIEGO (USA): Academic Press, 2015, roč. 113, MARCH, s. 152-158. ISSN 0147-6513. Dostupné z: https://dx.doi.org/10.1016/j.ecoenv.2014.11.018.

@article{1230107,
   author = {Bona, Mirco Dalla and Zounková, Radka and Merlanti, Roberta and Bláha, Luděk and De Liguoro, Marco},
   article_location = {SAN DIEGO (USA)},
   article_number = {MARCH},
   doi = {http://dx.doi.org/10.1016/j.ecoenv.2014.11.018},
   keywords = {Daphnia magna; Fluoroquinolones; Trimethoprim; Transgenerational toxicity},
   language = {eng},
   issn = {0147-6513},
   journal = {Ecotoxicology and Environmental Safety},
   title = {Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna},
   url = {http://www.sciencedirect.com/science/article/pii/S0147651314005302},
   volume = {113},
   year = {2015}
}

TY  - JOUR
ID  - 1230107
AU  - Bona, Mirco Dalla - Zounková, Radka - Merlanti, Roberta - Bláha, Luděk - De Liguoro, Marco
PY  - 2015
TI  - Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna
JF  - Ecotoxicology and Environmental Safety
VL  - 113
IS  - MARCH
SP  - 152-158
EP  - 152-158
PB  - Academic Press
SN  - 01476513
KW  - Daphnia magna
KW  - Fluoroquinolones
KW  - Trimethoprim
KW  - Transgenerational toxicity
UR  - http://www.sciencedirect.com/science/article/pii/S0147651314005302
L2  - http://www.sciencedirect.com/science/article/pii/S0147651314005302
N2  - Multigenerational tests on Daphnia magna were performed exposing two subsequent generation to enrofloxacin (EFX) and its metabolite ciprofloxacin (CPX), and to trimethoprim (TMP). Mortality rate of 100% and 50% was detected in F0 at concentrations of >= 13 mg L-1 (EFX) and 50 mg L-1 (TMP), respectively. In F1 with respect to FO, both for growth and reproduction, a worsening trend of the response with EFX, a similar response with CPX and an attenuating trend with TMP was observed. Furthermore, the lowest EC20 for reproduction inhibition (1.3 mg L-1) was calculated for F1 exposed to EFX. However, other experimentations, longer and more complex, are necessary in order to confirm that EFX is more hazardous to daphnids than CPX and TMP. EC50 measured for the three assayed antibacterials were in the 6.5-37 mg L-1 range therefore environmental unrealistic, except in case of exceptional contaminations that may occur in relation to poorly controlled wastewaters from pharmaceutical factories or excessive use of prophylactic treatments in aquaculture.
ER  -

BONA, Mirco Dalla, Radka ZOUNKOVÁ, Roberta MERLANTI, Luděk BLÁHA a Marco DE LIGUORO. Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna. \textit{Ecotoxicology and Environmental Safety}. SAN DIEGO (USA): Academic Press, 2015, roč.~113, MARCH, s.~152-158. ISSN~0147-6513. Dostupné z: https://dx.doi.org/10.1016/j.ecoenv.2014.11.018.

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