CD36 AA single nucleotide polymorphism (SNP) is associated with
decreased lipid taste perception in Tunisian obese women:
association with pro-inflammatory TNF-a GA and IL-6 GC
genotypes

a 2014

CD36 AA single nucleotide polymorphism (SNP) is associated with decreased lipid taste perception in Tunisian obese women: association with pro-inflammatory TNF-a GA and IL-6 GC genotypes

PLESNÍK, Jiří; Ines MRIZAK; Omar ŠERÝ; Amel ARFA; Mariem FEKIH et. al.

Základní údaje

Originální název

CD36 AA single nucleotide polymorphism (SNP) is associated with decreased lipid taste perception in Tunisian obese women: association with pro-inflammatory TNF-a GA and IL-6 GC genotypes

Název česky

CD36 AA jednonukleotidový polymormismus (SNP) je asociován se sníženou chuťovou percepcí lipidů u tuniských obézních žen: spojitost s prozánětlivými TNF-a GA and IL-6 GC genotypy

Autoři

PLESNÍK, Jiří (203 Česká republika, domácí); Ines MRIZAK (788 Tunisko); Omar ŠERÝ (203 Česká republika, garant, domácí); Amel ARFA (788 Tunisko); Mariem FEKIH (788 Tunisko); Ali BOUSLEMA (788 Tunisko); Monia ZAOUALI (788 Tunisko); Zouhair ZABKA (788 Tunisko) a Naim Akhtar KHAN (250 Francie)

Vydání

2014

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

10600 1.6 Biological sciences

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14310/14:00083198

Organizační jednotka

Přírodovědecká fakulta

ISSN

DOI

https://doi.org/10.1111/fcp.12064

Klíčová slova česky

obezity, lipidy, chuť, geny

Klíčová slova anglicky

obesity; lipids; taste; genes

Štítky

AKR

Změněno: 20. 4. 2016 14:26, Mgr. Jiří Plesník, Ph.D.

Anotace

V originále

We studied lingual detection thresholds for emulsions containing oleic acid in obese Tunisian women (n 203) using a three-alternative forced choice (3-AFC) method. Genotyping of the TNF-a (rs1800629), IL-6 (rs1800795) and CD36 (rs1761667) genes was performed to associate with lipid taste perception thresholds. The CD36 genotype distribution was as follows: GG (n 42), AG (n 102) and AA (n 59). Women with the CD36 GG genotype exhibited oral detection thresholds for oleic acid that were more than three times lower than those with the CD36 AA genotype. The present study confirms a high threshold of gustatory fat detection in obese women with the CD36 AA genotype, but there is no significant association with the IL-6 and TNF-a gene polymorphisms.

Citovat

PLESNÍK, Jiří; Ines MRIZAK; Omar ŠERÝ; Amel ARFA; Mariem FEKIH; Ali BOUSLEMA; Monia ZAOUALI; Zouhair ZABKA a Naim Akhtar KHAN. CD36 AA single nucleotide polymorphism (SNP) is associated with decreased lipid taste perception in Tunisian obese women: association with pro-inflammatory TNF-a GA and IL-6 GC genotypes. 2014. ISSN 1472-8206. Dostupné z: https://doi.org/10.1111/fcp.12064.

@proceedings{1301498,
   author = {Plesník, Jiří and Mrizak, Ines and Šerý, Omar and Arfa, Amel and Fekih, Mariem and Bouslema, Ali and Zaouali, Monia and Zabka, Zouhair and Khan, Naim Akhtar},
   doi = {https://doi.org/10.1111/fcp.12064},
   keywords = {obesity; lipids; taste; genes},
   language = {eng},
   title = {CD36 AA single nucleotide polymorphism (SNP) is associated with decreased lipid taste perception in Tunisian obese women: association with pro-inflammatory TNF-a GA and IL-6 GC genotypes},
   year = {2014}
}

TY  - CONF
ID  - 1301498
AU  - Plesník, Jiří - Mrizak, Ines - Šerý, Omar - Arfa, Amel - Fekih, Mariem - Bouslema, Ali - Zaouali, Monia - Zabka, Zouhair - Khan, Naim Akhtar
PY  - 2014
TI  - CD36 AA single nucleotide polymorphism (SNP) is associated with decreased lipid taste perception in Tunisian obese women: association with pro-inflammatory TNF-a GA and IL-6 GC genotypes
KW  - obesity
KW  - lipids
KW  - taste
KW  - genes
N2  - We studied lingual detection thresholds for emulsions containing oleic acid in obese Tunisian women (n 203) using a three-alternative forced choice (3-AFC) method. Genotyping of the TNF-a (rs1800629), IL-6 (rs1800795) and CD36 (rs1761667) genes was performed to associate with lipid taste perception thresholds. The CD36 genotype distribution was as follows: GG (n 42), AG (n 102) and AA (n 59). Women with the CD36 GG genotype exhibited oral detection thresholds for oleic acid that were more than three times lower than those with the CD36 AA genotype. The present study confirms a high threshold of gustatory fat detection in obese women with the CD36 AA genotype, but there is no significant association with the IL-6 and TNF-a gene polymorphisms.
ER  -

PLESNÍK, Jiří; Ines MRIZAK; Omar ŠERÝ; Amel ARFA; Mariem FEKIH; Ali BOUSLEMA; Monia ZAOUALI; Zouhair ZABKA a Naim Akhtar KHAN. \textit{CD36 AA single nucleotide polymorphism (SNP) is associated with decreased lipid taste perception in Tunisian obese women: association with pro-inflammatory TNF-a GA and IL-6 GC genotypes}. 2014. ISSN~1472-8206. Dostupné z: https://doi.org/10.1111/fcp.12064.

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