Cell proliferation on modified DLC thin films prepared by
plasma enhanced chemical vapor deposition

J 2015

Cell proliferation on modified DLC thin films prepared by plasma enhanced chemical vapor deposition

STOICA, Adrian; Anton MANAKHOV; Josef POLČÁK; Pavel ONDRAČKA; Vilma BURŠÍKOVÁ et. al.

Základní údaje

Originální název

Cell proliferation on modified DLC thin films prepared by plasma enhanced chemical vapor deposition

Autoři

STOICA, Adrian (642 Rumunsko, domácí); Anton MANAKHOV (643 Rusko, domácí); Josef POLČÁK (203 Česká republika); Pavel ONDRAČKA (203 Česká republika, domácí); Vilma BURŠÍKOVÁ (203 Česká republika, domácí); Renata ZAJÍČKOVÁ (203 Česká republika, garant, domácí); Jiřina MEDALOVÁ (203 Česká republika, domácí) a Lenka ZAJÍČKOVÁ (203 Česká republika, domácí)

Vydání

Biointerphases, Melville (USA), American Institute of Physics, 2015, 1934-8630

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10305 Fluids and plasma physics

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.105

Kód RIV

RIV/00216224:14740/15:00083399

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1116/1.4920978

UT WoS

000357195600038

EID Scopus

2-s2.0-84954584819

Klíčová slova anglicky

DLC thin films; Cell proliferation; plasma

Štítky

podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 13. 3. 2018 10:59, Mgr. Jiřina Medalová, Ph.D.

Anotace

V originále

Recently, diamondlike carbon (DLC) thin films have gained interest for biological applications, such as hip and dental prostheses or heart valves and coronary stents, thanks to their high strength and stability. However, the biocompatibility of the DLC is still questionable due to its low wettability and possible mechanical failure (delamination). In this work, DLC:N:O and DLC: SiOx thin films were comparatively investigated with respect to cell proliferation. Thin DLC films with an addition of N, O, and Si were prepared by plasma enhanced CVD from mixtures of methane, hydrogen, and hexamethyldisiloxane. The films were optically characterized by infrared spectroscopy and ellipsometry in UV-visible spectrum. The thickness and the optical properties were obtained from the ellipsometric measurements. Atomic composition of the films was determined by Rutherford backscattering spectroscopy combined with elastic recoil detection analysis and by x-ray photoelectron spectroscopy. The mechanical properties of the films were studied by depth sensing indentation technique. The number of cells that proliferate on the surface of the prepared DLC films and on control culture dishes were compared and correlated with the properties of as-deposited and aged films. The authors found that the level of cell proliferation on the coated dishes was high, comparable to the untreated (control) samples. The prepared DLC films were stable and no decrease of the biocompatibility was observed for the samples aged at ambient conditions.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

Přiložené soubory

ZVV_2015_1306316_Cell_proliferation.pdf

Požádat o autorskou verzi souboru

Citovat

STOICA, Adrian; Anton MANAKHOV; Josef POLČÁK; Pavel ONDRAČKA; Vilma BURŠÍKOVÁ; Renata ZAJÍČKOVÁ; Jiřina MEDALOVÁ a Lenka ZAJÍČKOVÁ. Cell proliferation on modified DLC thin films prepared by plasma enhanced chemical vapor deposition. Biointerphases. Melville (USA): American Institute of Physics, 2015, roč. 10, č. 2, s. nestránkováno, 9 s. ISSN 1934-8630. Dostupné z: https://dx.doi.org/10.1116/1.4920978.

@article{1306316,
   author = {Stoica, Adrian and Manakhov, Anton and Polčák, Josef and Ondračka, Pavel and Buršíková, Vilma and Zajíčková, Renata and Medalová, Jiřina and Zajíčková, Lenka},
   article_location = {Melville (USA)},
   article_number = {2},
   doi = {http://dx.doi.org/10.1116/1.4920978},
   keywords = {DLC thin films; Cell proliferation; plasma},
   language = {eng},
   issn = {1934-8630},
   journal = {Biointerphases},
   title = {Cell proliferation on modified DLC thin films prepared by plasma enhanced chemical vapor deposition},
   url = {http://www.ncbi.nlm.nih.gov/pubmed/25967153},
   volume = {10},
   year = {2015}
}

TY  - JOUR
ID  - 1306316
AU  - Stoica, Adrian - Manakhov, Anton - Polčák, Josef - Ondračka, Pavel - Buršíková, Vilma - Zajíčková, Renata - Medalová, Jiřina - Zajíčková, Lenka
PY  - 2015
TI  - Cell proliferation on modified DLC thin films prepared by plasma enhanced chemical vapor deposition
JF  - Biointerphases
VL  - 10
IS  - 2
SP  - nestránkováno
EP  - nestránkováno
PB  - American Institute of Physics
SN  - 19348630
KW  - DLC thin films
KW  - Cell proliferation
KW  - plasma
UR  - http://www.ncbi.nlm.nih.gov/pubmed/25967153
L2  - http://www.ncbi.nlm.nih.gov/pubmed/25967153
N2  - Recently, diamondlike carbon (DLC) thin films have gained interest for biological applications, such as hip and dental prostheses or heart valves and coronary stents, thanks to their high strength and stability. However, the biocompatibility of the DLC is still questionable due to its low wettability and possible mechanical failure (delamination). In this work, DLC:N:O and DLC: SiOx thin films were comparatively investigated with respect to cell proliferation. Thin DLC films with an addition of N, O, and Si were prepared by plasma enhanced CVD from mixtures of methane, hydrogen, and hexamethyldisiloxane. The films were optically characterized by infrared spectroscopy and ellipsometry in UV-visible spectrum. The thickness and the optical properties were obtained from the ellipsometric measurements. Atomic composition of the films was determined by Rutherford backscattering spectroscopy combined with elastic recoil detection analysis and by x-ray photoelectron spectroscopy. The mechanical properties of the films were studied by depth sensing indentation technique. The number of cells that proliferate on the surface of the prepared DLC films and on control culture dishes were compared and correlated with the properties of as-deposited and aged films. The authors found that the level of cell proliferation on the coated dishes was high, comparable to the untreated (control) samples. The prepared DLC films were stable and no decrease of the biocompatibility was observed for the samples aged at ambient conditions.
ER  -

STOICA, Adrian; Anton MANAKHOV; Josef POLČÁK; Pavel ONDRAČKA; Vilma BURŠÍKOVÁ; Renata ZAJÍČKOVÁ; Jiřina MEDALOVÁ a Lenka ZAJÍČKOVÁ. Cell proliferation on modified DLC thin films prepared by plasma enhanced chemical vapor deposition. \textit{Biointerphases}. Melville (USA): American Institute of Physics, 2015, roč.~10, č.~2, s.~nestránkováno, 9 s. ISSN~1934-8630. Dostupné z: https://dx.doi.org/10.1116/1.4920978.

Přehled o publikaci