Volumetric modulated arc therapy for hippocampal-sparing
radiotherapy in transformed low-grade glioma: A treatment
planning case report

J 2015

Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report

KAZDA, Tomáš, Petr POSPÍŠIL, M. VRZAL, O. SEVELA, T. PROCHAZKA et. al.

Základní údaje

Originální název

Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report

Autoři

KAZDA, Tomáš (203 Česká republika, garant, domácí), Petr POSPÍŠIL (203 Česká republika, domácí), M. VRZAL (203 Česká republika), O. SEVELA (203 Česká republika), T. PROCHAZKA (203 Česká republika), Radim JANČÁLEK (203 Česká republika, domácí), Pavel ŠLAMPA (203 Česká republika, domácí) a N.N. LAACK (840 Spojené státy)

Vydání

CANCER RADIOTHERAPIE, BRIDGEWATER, ELSEVIER, 2015, 1278-3218

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.299

Kód RIV

RIV/00216224:14110/15:00083613

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.canrad.2014.11.013

UT WoS

000355641500005

Klíčová slova anglicky

Hippocampus; Astrocytoma; Neurocognition; Cranial irradiation

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 25. 8. 2015 13:36, Jana Dvořáková

Anotace

V originále

Timing of radiotherapy for low-grade gliomas is still controversial due to concerns of possible adverse late effects. Prevention of possible late cognitive sequelae by hippocampal avoidance has shown promise in phase II trials. A patient with progressive low-grade glioma with gradual dedifferentiation into anaplastic astrocytoma is presented along with description of radiotherapy planning process attempting to spare the hippocampus. To our knowledge, this is the first described case using volumetric modulated arc technique to spare hippocampus during transformed low-grade glioma radiotherapy. Using modern intensity-modulated radiotherapy systems it is possible to selectively spare hippocampus together with other standard organs at risk. For selected patients, an attempt to spare hippocampus can be considered as long as other dose characteristics are not significantly compromised compared to standard treatment plan created without any effort to avoid hippocampus.

Citovat

KAZDA, Tomáš, Petr POSPÍŠIL, M. VRZAL, O. SEVELA, T. PROCHAZKA, Radim JANČÁLEK, Pavel ŠLAMPA a N.N. LAACK. Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report. CANCER RADIOTHERAPIE. BRIDGEWATER: ELSEVIER, 2015, roč. 19, č. 3, s. 187-191. ISSN 1278-3218. Dostupné z: https://dx.doi.org/10.1016/j.canrad.2014.11.013.

@article{1309114,
   author = {Kazda, Tomáš and Pospíšil, Petr and Vrzal, M. and Sevela, O. and Prochazka, T. and Jančálek, Radim and Šlampa, Pavel and Laack, N.N.},
   article_location = {BRIDGEWATER},
   article_number = {3},
   doi = {http://dx.doi.org/10.1016/j.canrad.2014.11.013},
   keywords = {Hippocampus; Astrocytoma; Neurocognition; Cranial irradiation},
   language = {eng},
   issn = {1278-3218},
   journal = {CANCER RADIOTHERAPIE},
   title = {Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report},
   volume = {19},
   year = {2015}
}

TY  - JOUR
ID  - 1309114
AU  - Kazda, Tomáš - Pospíšil, Petr - Vrzal, M. - Sevela, O. - Prochazka, T. - Jančálek, Radim - Šlampa, Pavel - Laack, N.N.
PY  - 2015
TI  - Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report
JF  - CANCER RADIOTHERAPIE
VL  - 19
IS  - 3
SP  - 187-191
EP  - 187-191
PB  - ELSEVIER
SN  - 12783218
KW  - Hippocampus
KW  - Astrocytoma
KW  - Neurocognition
KW  - Cranial irradiation
N2  - Timing of radiotherapy for low-grade gliomas is still controversial due to concerns of possible adverse late effects. Prevention of possible late cognitive sequelae by hippocampal avoidance has shown promise in phase II trials. A patient with progressive low-grade glioma with gradual dedifferentiation into anaplastic astrocytoma is presented along with description of radiotherapy planning process attempting to spare the hippocampus. To our knowledge, this is the first described case using volumetric modulated arc technique to spare hippocampus during transformed low-grade glioma radiotherapy. Using modern intensity-modulated radiotherapy systems it is possible to selectively spare hippocampus together with other standard organs at risk. For selected patients, an attempt to spare hippocampus can be considered as long as other dose characteristics are not significantly compromised compared to standard treatment plan created without any effort to avoid hippocampus.
ER  -

KAZDA, Tomáš, Petr POSPÍŠIL, M. VRZAL, O. SEVELA, T. PROCHAZKA, Radim JANČÁLEK, Pavel ŠLAMPA a N.N. LAACK. Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report. \textit{CANCER RADIOTHERAPIE}. BRIDGEWATER: ELSEVIER, 2015, roč.~19, č.~3, s.~187-191. ISSN~1278-3218. Dostupné z: https://dx.doi.org/10.1016/j.canrad.2014.11.013.

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