Nanostructured gold electrodes for determination of glucose in
blood

D 2015

Nanostructured gold electrodes for determination of glucose in blood

FARKA, Zdeněk, Tomáš JUŘÍK, David KOVÁŘ, Pavel PODEŠVA, František FORET et. al.

Základní údaje

Originální název

Nanostructured gold electrodes for determination of glucose in blood

Autoři

FARKA, Zdeněk (203 Česká republika, domácí), Tomáš JUŘÍK (203 Česká republika, domácí), David KOVÁŘ (203 Česká republika, domácí), Pavel PODEŠVA (203 Česká republika, domácí), František FORET (203 Česká republika, domácí) a Petr SKLÁDAL (203 Česká republika, garant, domácí)

Vydání

Brno, CECE 2015, od s. 54-57, 4 s. 2015

Nakladatel

Institute of Analytical Chemistry of the CAS, v. v. i.

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

elektronická verze "online"

Odkazy

URL

Kód RIV

RIV/00216224:14740/15:00083973

Organizační jednotka

Středoevropský technologický institut

ISBN

978-80-904959-3-7

Klíčová slova anglicky

gold nanostructures; gelatin template; glucose electrooxidation; non-enzymatic sensor; blood analysis

Příznaky

Mezinárodní význam

Změněno: 27. 9. 2015 18:44, doc. Mgr. Zdeněk Farka, Ph.D.

Anotace

V originále

Fast and sensitive devices for monitoring of glucose are crucial in today’s medicine. Most of the commercial glucometers are currently based on enzymatic catalysis which provides reasonable sensitivity but has a drawback in limited enzyme stability. With the development of novel surfaces, new generation of non-enzymatic sensors characterized by high sensitivity and stability is emerging. In this work, gelatin-templated nanostructured gold electrodes were developed and applied for non-enzymatic glucose determination. The analysis was done by direct electrochemical oxidation during cyclic voltammetry and amperometry with the limit of detection at 1.3 µM. The ability to detect physiological levels glucose in presence of interferents was demonstrated on deproteinized human blood serum.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

Citovat

FARKA, Zdeněk, Tomáš JUŘÍK, David KOVÁŘ, Pavel PODEŠVA, František FORET a Petr SKLÁDAL. Nanostructured gold electrodes for determination of glucose in blood. Online. In František Foret, Jana Křenková, Iveta Drobníková, Karel Klepárník. CECE 2015. Brno: Institute of Analytical Chemistry of the CAS, v. v. i., 2015, s. 54-57. ISBN 978-80-904959-3-7.

@inproceedings{1312088,
   author = {Farka, Zdeněk and Juřík, Tomáš and Kovář, David and Podešva, Pavel and Foret, František and Skládal, Petr},
   address = {Brno},
   booktitle = {CECE 2015},
   editor = {František Foret, Jana Křenková, Iveta Drobníková, Karel Klepárník},
   keywords = {gold nanostructures; gelatin template; glucose electrooxidation; non-enzymatic sensor; blood analysis},
   howpublished = {elektronická verze "online"},
   language = {eng},
   location = {Brno},
   isbn = {978-80-904959-3-7},
   pages = {54-57},
   publisher = {Institute of Analytical Chemistry of the CAS, v. v. i.},
   title = {Nanostructured gold electrodes for determination of glucose in blood},
   url = {http://www.ce-ce.org/CECE2015/CECE%202015%20Proceedings_full.pdf#page=55},
   year = {2015}
}

TY  - JOUR
ID  - 1312088
AU  - Farka, Zdeněk - Juřík, Tomáš - Kovář, David - Podešva, Pavel - Foret, František - Skládal, Petr
PY  - 2015
TI  - Nanostructured gold electrodes for determination of glucose in blood
PB  - Institute of Analytical Chemistry of the CAS, v. v. i.
CY  - Brno
SN  - 9788090495937
KW  - gold nanostructures
KW  - gelatin template
KW  - glucose electrooxidation
KW  - non-enzymatic sensor
KW  - blood analysis
UR  - http://www.ce-ce.org/CECE2015/CECE%202015%20Proceedings_full.pdf#page=55
N2  - Fast and sensitive devices for monitoring of glucose are crucial in today’s medicine. Most of the commercial glucometers are currently based on enzymatic catalysis which provides reasonable sensitivity but has a drawback in limited enzyme stability. With the development of novel surfaces, new generation of non-enzymatic sensors characterized by high sensitivity and stability is emerging. In this work, gelatin-templated nanostructured gold electrodes were developed and applied for non-enzymatic glucose determination. The analysis was done by direct electrochemical oxidation during cyclic voltammetry and amperometry with the limit of detection at 1.3 µM. The ability to detect physiological levels glucose in presence of interferents was demonstrated on deproteinized human blood serum.
ER  -

FARKA, Zdeněk, Tomáš JUŘÍK, David KOVÁŘ, Pavel PODEŠVA, František FORET a Petr SKLÁDAL. Nanostructured gold electrodes for determination of glucose in blood. Online. In František Foret, Jana Křenková, Iveta Drobníková, Karel Klepárník. \textit{CECE 2015}. Brno: Institute of Analytical Chemistry of the CAS, v. v. i., 2015, s.~54-57. ISBN~978-80-904959-3-7.

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