HYRŠL, Pavel, Pavel DOBEŠ, Badrul AREFIN, Jakub BERKA, Lucie KUČEROVÁ, Robert MARKUS, Zhi WANG, Michal ŽUROVEC a Ulrich THEOPOLD. Insect immunity after invasion of entomopathogenic nematodes. In Workshop: At the crossroads between insect immunology, physiology and ecology. 2015.
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Základní údaje
Originální název Insect immunity after invasion of entomopathogenic nematodes
Název česky Insect immunity after invasion of entomopathogenic nematodes
Autoři HYRŠL, Pavel (203 Česká republika, garant, domácí), Pavel DOBEŠ (203 Česká republika, domácí), Badrul AREFIN (752 Švédsko), Jakub BERKA (203 Česká republika, domácí), Lucie KUČEROVÁ (752 Švédsko), Robert MARKUS (752 Švédsko), Zhi WANG (752 Švédsko), Michal ŽUROVEC (203 Česká republika) a Ulrich THEOPOLD (752 Švédsko).
Vydání Workshop: At the crossroads between insect immunology, physiology and ecology, 2015.
Další údaje
Originální jazyk angličtina
Typ výsledku Konferenční abstrakt
Obor 30102 Immunology
Stát vydavatele Česká republika
Utajení není předmětem státního či obchodního tajemství
Kód RIV RIV/00216224:14310/15:00080483
Organizační jednotka Přírodovědecká fakulta
Klíčová slova česky imunita; Drosophila; hmyz
Klíčová slova anglicky immunity; Drosophila; insect
Změnil Změnil: doc. RNDr. Pavel Hyršl, Ph.D., učo 9982. Změněno: 19. 10. 2015 18:32.
Anotace
Entomopathogenic nematodes and their associated bacteria comprise together highly pathogenic complex able to invade and kill insect host within two days. Both bacteria and nematodes produce variety of factors interacting with insect immune system that help to overcome host defences. The tripartite model (Drosophila, nematodes, bacteria) was established and used to show an immune function for candidate genes using different Drosophila mutants or RNAi lines with defects in clotting or other branches of the immune system. We demonstrated an immune function during nematode infection for known clotting enzymes and substrates, recognition molecules, eicosanoids etc. In conclusion, we show that the Heterorhabditis/Photorhabdus infection model is suitable to identify novel regulators of innate immunity and we bring evidence of coagulation immune function in insects against nematode infection. Our research is supported by research grants from the Swedish Foundation for International Cooperation in Research and Higher Education (STINT) and by grant from Ministry of Agriculture of Czech Republic (NAZV-KUS QJ1210047).
Anotace česky
Entomopathogenic nematodes and their associated bacteria comprise together highly pathogenic complex able to invade and kill insect host within two days. Both bacteria and nematodes produce variety of factors interacting with insect immune system that help to overcome host defences. The tripartite model (Drosophila, nematodes, bacteria) was established and used to show an immune function for candidate genes using different Drosophila mutants or RNAi lines with defects in clotting or other branches of the immune system. We demonstrated an immune function during nematode infection for known clotting enzymes and substrates, recognition molecules, eicosanoids etc. In conclusion, we show that the Heterorhabditis/Photorhabdus infection model is suitable to identify novel regulators of innate immunity and we bring evidence of coagulation immune function in insects against nematode infection. Our research is supported by research grants from the Swedish Foundation for International Cooperation in Research and Higher Education (STINT) and by grant from Ministry of Agriculture of Czech Republic (NAZV-KUS QJ1210047).
Návaznosti
QJ1210047, projekt VaVNázev: Vývoj nových prostředků pro podporu imunity včel, prevenci a léčbu včelích onemocnění (Akronym: Probiotika - imunita včel)
Investor: Ministerstvo zemědělství ČR, Vývoj nových prostředků pro podporu imunity včel, prevenci a léčbu včelích onemocnění
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