2015
Insect immunity after invasion of entomopathogenic nematodes
HYRŠL, Pavel, Pavel DOBEŠ, Badrul AREFIN, Jakub BERKA, Lucie KUČEROVÁ et. al.Základní údaje
Originální název
Insect immunity after invasion of entomopathogenic nematodes
Název česky
Insect immunity after invasion of entomopathogenic nematodes
Autoři
HYRŠL, Pavel (203 Česká republika, garant, domácí), Pavel DOBEŠ (203 Česká republika, domácí), Badrul AREFIN (752 Švédsko), Jakub BERKA (203 Česká republika, domácí), Lucie KUČEROVÁ (752 Švédsko), Robert MARKUS (752 Švédsko), Zhi WANG (752 Švédsko), Michal ŽUROVEC (203 Česká republika) a Ulrich THEOPOLD (752 Švédsko)
Vydání
Workshop: At the crossroads between insect immunology, physiology and ecology, 2015
Další údaje
Jazyk
angličtina
Typ výsledku
Konferenční abstrakt
Obor
30102 Immunology
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Kód RIV
RIV/00216224:14310/15:00080483
Organizační jednotka
Přírodovědecká fakulta
Klíčová slova česky
imunita; Drosophila; hmyz
Klíčová slova anglicky
immunity; Drosophila; insect
Změněno: 19. 10. 2015 18:32, doc. RNDr. Pavel Hyršl, Ph.D.
V originále
Entomopathogenic nematodes and their associated bacteria comprise together highly pathogenic complex able to invade and kill insect host within two days. Both bacteria and nematodes produce variety of factors interacting with insect immune system that help to overcome host defences. The tripartite model (Drosophila, nematodes, bacteria) was established and used to show an immune function for candidate genes using different Drosophila mutants or RNAi lines with defects in clotting or other branches of the immune system. We demonstrated an immune function during nematode infection for known clotting enzymes and substrates, recognition molecules, eicosanoids etc. In conclusion, we show that the Heterorhabditis/Photorhabdus infection model is suitable to identify novel regulators of innate immunity and we bring evidence of coagulation immune function in insects against nematode infection. Our research is supported by research grants from the Swedish Foundation for International Cooperation in Research and Higher Education (STINT) and by grant from Ministry of Agriculture of Czech Republic (NAZV-KUS QJ1210047).
Česky
Entomopathogenic nematodes and their associated bacteria comprise together highly pathogenic complex able to invade and kill insect host within two days. Both bacteria and nematodes produce variety of factors interacting with insect immune system that help to overcome host defences. The tripartite model (Drosophila, nematodes, bacteria) was established and used to show an immune function for candidate genes using different Drosophila mutants or RNAi lines with defects in clotting or other branches of the immune system. We demonstrated an immune function during nematode infection for known clotting enzymes and substrates, recognition molecules, eicosanoids etc. In conclusion, we show that the Heterorhabditis/Photorhabdus infection model is suitable to identify novel regulators of innate immunity and we bring evidence of coagulation immune function in insects against nematode infection. Our research is supported by research grants from the Swedish Foundation for International Cooperation in Research and Higher Education (STINT) and by grant from Ministry of Agriculture of Czech Republic (NAZV-KUS QJ1210047).
Návaznosti
| QJ1210047, projekt VaV |
|