J 2017

Cleft palate caused by congenital teratoma

VEYSSIÈRE, Alexis, Libor STREIT, Hamady TRAORÉ a Hervé BÉNATEAU

Základní údaje

Originální název

Cleft palate caused by congenital teratoma

Autoři

VEYSSIÈRE, Alexis, Libor STREIT, Hamady TRAORÉ a Hervé BÉNATEAU

Vydání

Paediatrics and International Child Health, Abingdon, Taylor & Francis LTD, 2017, 2046-9047

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 1.528

Organizační jednotka

Lékařská fakulta

UT WoS

000395629100012

Klíčová slova anglicky

Benign teratoma; Cleft palate

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 16. 3. 2018 15:13, Soňa Böhmová

Anotace

V originále

A cleft palate results from incomplete fusion of the lateral palatine processes, the median nasal septum and the median palatine process. This case report describes a rare case of congenital teratoma originating from the nasal septum that may have interfered with the fusion of the palatal shelves during embryonic development, resulting in a cleft palate. An infant girl was born at 40 weeks of gestation weighing 3020 g with a complete cleft palate associated with a large central nasopharyngeal tumour. Computed tomography (CT) of the head showed a well defined mass of mixed density. The tumour was attached to the nasal septum in direct contact with the cleft palate. A biopsy confirmed the teratoma. Tumour resection was performed at 5 months, soft palate reconstruction at 7 months and hard palate closure at 14 months. There was no sign of local recurrence 1 year later. Most teratomas are benign and the prognosis is usually good. However, recurrence is not rare if germ cell carcinomatous foci are present within the teratoma. For these reasons, we advocate the use of a two-stage procedure in which closure of the cleft palate is postponed until histological examination confirms complete excision of the teratoma.