FEDURCO, Milan, Jana GREGOROVÁ, Kristýna ŠEBRLOVÁ, Jana KANTOROVÁ, Ondřej PEŠ, Roland BAUR, Erwin SIGEL and Eva TÁBORSKÁ. Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. Biochemistry Research International. New York: Hindawi Publishing Corporation, 2015, vol. 2015, UNSP 617620, p. 1-9. ISSN 2090-2247. Available from: https://dx.doi.org/10.1155/2015/617620. |
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@article{1318521, author = {Fedurco, Milan and Gregorová, Jana and Šebrlová, Kristýna and Kantorová, Jana and Peš, Ondřej and Baur, Roland and Sigel, Erwin and Táborská, Eva}, article_location = {New York}, article_number = {UNSP 617620}, doi = {http://dx.doi.org/10.1155/2015/617620}, keywords = {Escholzia californica; alkaloids; gaba receptors; mass spectrometry}, language = {eng}, issn = {2090-2247}, journal = {Biochemistry Research International}, title = {Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors}, volume = {2015}, year = {2015} }
TY - JOUR ID - 1318521 AU - Fedurco, Milan - Gregorová, Jana - Šebrlová, Kristýna - Kantorová, Jana - Peš, Ondřej - Baur, Roland - Sigel, Erwin - Táborská, Eva PY - 2015 TI - Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors JF - Biochemistry Research International VL - 2015 IS - UNSP 617620 SP - 1-9 EP - 1-9 PB - Hindawi Publishing Corporation SN - 20902247 KW - Escholzia californica KW - alkaloids KW - gaba receptors KW - mass spectrometry N2 - The California poppy (Eschscholzia californica Cham.) contains a variety of natural compounds including several alkaloids found exclusively in this plant. Because of the sedative, anxiolytic, and analgesic effects, this herb is currently sold in pharmacies in many countries. However, our understanding of these biological effects at the molecular level is still lacking. Alkaloids detected in E. californica could be hypothesized to act at GABAA receptors, which are widely expressed in the brain mainly at the inhibitory interneurons. ER -
FEDURCO, Milan, Jana GREGOROVÁ, Kristýna ŠEBRLOVÁ, Jana KANTOROVÁ, Ondřej PEŠ, Roland BAUR, Erwin SIGEL and Eva TÁBORSKÁ. Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. \textit{Biochemistry Research International}. New York: Hindawi Publishing Corporation, 2015, vol.~2015, UNSP 617620, p.~1-9. ISSN~2090-2247. Available from: https://dx.doi.org/10.1155/2015/617620.
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