FEDURCO, Milan, Jana GREGOROVÁ, Kristýna ŠEBRLOVÁ, Jana KANTOROVÁ, Ondřej PEŠ, Roland BAUR, Erwin SIGEL and Eva TÁBORSKÁ. Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. Biochemistry Research International. New York: Hindawi Publishing Corporation, 2015, vol. 2015, UNSP 617620, p. 1-9. ISSN 2090-2247. Available from: https://dx.doi.org/10.1155/2015/617620.
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Basic information
Original name Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors
Authors FEDURCO, Milan (756 Switzerland), Jana GREGOROVÁ (203 Czech Republic, belonging to the institution), Kristýna ŠEBRLOVÁ (203 Czech Republic, belonging to the institution), Jana KANTOROVÁ (203 Czech Republic, belonging to the institution), Ondřej PEŠ (203 Czech Republic, belonging to the institution), Roland BAUR (756 Switzerland), Erwin SIGEL (756 Switzerland) and Eva TÁBORSKÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Biochemistry Research International, New York, Hindawi Publishing Corporation, 2015, 2090-2247.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/15:00084850
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1155/2015/617620
UT WoS 000362645500001
Keywords in English Escholzia californica; alkaloids; gaba receptors; mass spectrometry
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 26/11/2015 12:23.
Abstract
The California poppy (Eschscholzia californica Cham.) contains a variety of natural compounds including several alkaloids found exclusively in this plant. Because of the sedative, anxiolytic, and analgesic effects, this herb is currently sold in pharmacies in many countries. However, our understanding of these biological effects at the molecular level is still lacking. Alkaloids detected in E. californica could be hypothesized to act at GABAA receptors, which are widely expressed in the brain mainly at the inhibitory interneurons.
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