| BRÁZDIL, Milan, Jan CIMBÁLNÍK, Robert ROMAN, Daniel Joel SHAW, Matt M. STEAD, Pavel DANIEL, Pavel JURÁK a Josef HALÁMEK. Impact of cognitive stimulation on ripples within human epileptic and non-epileptic hippocampus. BMC Neuroscience. LONDON: Biomed Central Ltd., 2015, roč. 16, july, s. "nestránkováno", 9 s. ISSN 1471-2202. Dostupné z: https://dx.doi.org/10.1186/s12868-015-0184-0. |
Další formáty:
BibTeX
LaTeX
RIS
@article{1318806,
author = {Brázdil, Milan and Cimbálník, Jan and Roman, Robert and Shaw, Daniel Joel and Stead, Matt M. and Daniel, Pavel and Jurák, Pavel and Halámek, Josef},
article_location = {LONDON},
article_number = {july},
doi = {http://dx.doi.org/10.1186/s12868-015-0184-0},
keywords = {High-frequency oscillations; Hippocampal ripples; Epilepsy; Human cognition},
language = {eng},
issn = {1471-2202},
journal = {BMC Neuroscience},
title = {Impact of cognitive stimulation on ripples within human epileptic and non-epileptic hippocampus},
url = {http://www.biomedcentral.com/content/pdf/s12868-015-0184-0.pdf},
volume = {16},
year = {2015}
}
TY - JOUR
ID - 1318806
AU - Brázdil, Milan - Cimbálník, Jan - Roman, Robert - Shaw, Daniel Joel - Stead, Matt M. - Daniel, Pavel - Jurák, Pavel - Halámek, Josef
PY - 2015
TI - Impact of cognitive stimulation on ripples within human epileptic and non-epileptic hippocampus
JF - BMC Neuroscience
VL - 16
IS - july
SP - "nestránkováno"
EP - "nestránkováno"
PB - Biomed Central Ltd.
SN - 14712202
KW - High-frequency oscillations
KW - Hippocampal ripples
KW - Epilepsy
KW - Human cognition
UR - http://www.biomedcentral.com/content/pdf/s12868-015-0184-0.pdf
L2 - http://www.biomedcentral.com/content/pdf/s12868-015-0184-0.pdf
N2 - Background: Until now there has been no way of distinguishing between physiological and epileptic hippocampal ripples in intracranial recordings. In the present study we addressed this by investigating the effect of cognitive stimulation on interictal high frequency oscillations in the ripple range (80-250 Hz) within epileptic (EH) and non-epileptic hippocampus (NH). Methods: We analyzed depth EEG recordings in 10 patients with intractable epilepsy, in whom hippocampal activity was recorded initially during quiet wakefulness and subsequently during a simple cognitive task. Using automated detection of ripples based on amplitude of the power envelope, we analyzed ripple rate (RR) in the cognitive and resting period, within EH and NH. Results: Compared to quiet wakefulness we observed a significant reduction of RR during cognitive stimulation in EH, while it remained statistically marginal in NH. Further, we investigated the direct impact of cognitive stimuli on ripples (i.e. immediately post-stimulus), which showed a transient statistically significant suppression of ripples in the first second after stimuli onset in NH only. Conclusion: Our results point to a differential reactivity of ripples within EH and NH to cognitive stimulation.
ER -
BRÁZDIL, Milan, Jan CIMBÁLNÍK, Robert ROMAN, Daniel Joel SHAW, Matt M. STEAD, Pavel DANIEL, Pavel JURÁK a Josef HALÁMEK. Impact of cognitive stimulation on ripples within human epileptic and non-epileptic hippocampus. \textit{BMC Neuroscience}. LONDON: Biomed Central Ltd., 2015, roč.~16, july, s.~''nestránkováno'', 9 s. ISSN~1471-2202. Dostupné z: https://dx.doi.org/10.1186/s12868-015-0184-0.
|
