2015
Addenbrooke's Cognitive Examination and Individual Domain Cut-Off Scores for Discriminating between Different Cognitive Subtypes of Parkinson's Disease
BERÁNKOVÁ, Dagmar, Eva JANOUŠOVÁ, Martina MRAČKOVÁ, Ilona ELIÁŠOVÁ, Milena KOŠŤÁLOVÁ et. al.Základní údaje
Originální název
Addenbrooke's Cognitive Examination and Individual Domain Cut-Off Scores for Discriminating between Different Cognitive Subtypes of Parkinson's Disease
Autoři
BERÁNKOVÁ, Dagmar (203 Česká republika, domácí), Eva JANOUŠOVÁ (203 Česká republika, domácí), Martina MRAČKOVÁ (203 Česká republika, domácí), Ilona ELIÁŠOVÁ (203 Česká republika, domácí), Milena KOŠŤÁLOVÁ (203 Česká republika, domácí), Světlana SKUTILOVÁ (203 Česká republika, domácí) a Irena REKTOROVÁ (203 Česká republika, garant, domácí)
Vydání
Parkinson’s Disease, New York, Hindawi Publishing Corporation, 2015, 2090-8083
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30000 3. Medical and Health Sciences
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 1.722
Kód RIV
RIV/00216224:14110/15:00085053
Organizační jednotka
Lékařská fakulta
UT WoS
000360499500001
Klíčová slova anglicky
REVISED ACE-R; DIAGNOSTIC-CRITERIA; IMPAIRMENT; DEMENTIA; VALIDATION; ACCURACY; UTILITY; COHORT
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 15. 12. 2015 14:40, Ing. Mgr. Věra Pospíšilíková
Anotace
V originále
Objective. The main aim of this study was to verify the sensitivity and specificity of Addenbrooke's Cognitive Examination-Revised (ACE-R) in discriminating between Parkinson's disease (PD) with normal cognition (PD-NC) and PD withmild cognitive impairment (PD-MCI) and between PD-MCI and PD with dementia (PD-D). We also evaluated how ACE-R correlates with neuropsychological cognitive tests in PD. Methods. We examined three age-matched groups of PD patients diagnosed according to the Movement Disorder Society Task Force criteria: PD-NC, PD-MCI, and PD-D. ROC analysis was used to establish specific cut-off scores of ACE-R and its domains. Correlation analyses were performed between ACE-R and its subtests with relevant neuropsychological tests. Results. Statistically significant differences between groups were demonstrated in global ACE-R scores and subscores, except in the language domain. ACE-R cut-off score of 88.5 points discriminated best between PD-MCI and PD-NC (sensitivity 0.68, specificity 0.91); ACE-R of 82.5 points distinguished best between PD-MCI and PD-D (sensitivity 0.70, specificity 0.73). The verbal fluency domain of ACE-R demonstrated the best discrimination between PD-NC and PD-MCI (cut-off score 11.5; sensitivity 0.70, specificity 0.73) while the orientation/attention subscore was best between PD-MCI and PD-D (cut-off score 15.5; sensitivity 0.90, specificity 0.97). ACE-R scores except for ACE-R language correlated with specific cognitive tests of interest.
Návaznosti
ED1.1.00/02.0068, projekt VaV |
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NT13499, projekt VaV |
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