2015
Clinical presentation and outcome by age categories in acute heart failure: results from an international observational cohort
TEIXEIRA, Antonio, Jiří PAŘENICA, Jin Joo PARK, Shiro ISHIHARA, Khalid F. ALHABIB et. al.Základní údaje
Originální název
Clinical presentation and outcome by age categories in acute heart failure: results from an international observational cohort
Autoři
TEIXEIRA, Antonio (250 Francie), Jiří PAŘENICA (203 Česká republika, garant, domácí), Jin Joo PARK (410 Korejská republika), Shiro ISHIHARA (392 Japonsko), Khalid F. ALHABIB (682 Saúdská Arábie), Said LARIBI (250 Francie), Aldo MAGGIONI (380 Itálie), Òscar MIRÓ (724 Španělsko), Naoki SATO (392 Japonsko), Katsuya KAJIMOTO (392 Japonsko), Alain COHEN-SOLAL (250 Francie), Enrique FAIRMAN (32 Argentina), Johan LASSUS (246 Finsko), Christian MUELLER (756 Švýcarsko), William F. PEACOCK (840 Spojené státy), James L. Jr. JANUZZI (840 Spojené státy), Dong-Ju CHOI (410 Korejská republika), Patrick PLAISANCE (250 Francie), Jindřich ŠPINAR (203 Česká republika, domácí), Alexandre MEBAZAA (250 Francie) a Etienne GAYAT (250 Francie)
Vydání
European Journal of heart Failure, Hoboken, Wiley-Blackwell, 2015, 1388-9842
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 5.135
Kód RIV
RIV/00216224:14110/15:00085125
Organizační jednotka
Lékařská fakulta
UT WoS
000366415100006
Klíčová slova anglicky
Heart failure;Heart failure with reduced ejection fraction;Elderly;Cardiac risk factors and prevention;Diabetes;Heart failure with preserved ejection fraction
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 7. 1. 2016 17:21, Soňa Böhmová
Anotace
V originále
To assess, according to age groups, patients' characteristics according to region of origin, the chronic therapeutic management, prognostic utility of clinical variables, and natriuretic peptides. Methods and results The GREAT registry consisted of patients identified as presenting with acute heart failure at the emergency department. Four groups of patients were defined according to age: the young patient group (<65 years); ‘middle-old’ (65–74 years), ‘old-old’ (75–84 years) and the ‘oldest-old’ (85–94 years). Follow-up at 1 year was performed via personal contact or national data registries at 1 year. Dataset consisted of 14 758 patients aged up to 95 years, with the ‘oldest-old’ group being more prevalent in North America and Western Europe. The 30-day mortality rate were, respectively, 8.1%, 8.9%, 10.3%, and 16.3% among the four age groups and 1-year mortality rates were, respectively, 3.1%, 17.1%, 24.7%, and 39.9%. Chronic heart failure treatment was less frequently administered with age (percentage of the ‘fully treated’ group was 14% in the ‘young’ compared with 2% in the ‘oldest-old’ patient group). Reduced left ventricular ejection fraction was present in 70%, 62.3%, 52.5%, and 46.8% among the four age groups, respectively. The prognostic utility of most variables for short- and long-term outcome was attenuated with age, with the exception of natriuretic peptides. Conclusion This study found a large heterogeneity in age among geographic regions and that the eldest are less likely to be treated in accordance with recommendations of current heart failure guidelines. Natriuretic peptide concentrations retained prognostic value in patients across age strata.