J 2015

Clinical presentation and outcome by age categories in acute heart failure: results from an international observational cohort

TEIXEIRA, Antonio, Jiří PAŘENICA, Jin Joo PARK, Shiro ISHIHARA, Khalid F. ALHABIB et. al.

Základní údaje

Originální název

Clinical presentation and outcome by age categories in acute heart failure: results from an international observational cohort

Autoři

TEIXEIRA, Antonio (250 Francie), Jiří PAŘENICA (203 Česká republika, garant, domácí), Jin Joo PARK (410 Korejská republika), Shiro ISHIHARA (392 Japonsko), Khalid F. ALHABIB (682 Saúdská Arábie), Said LARIBI (250 Francie), Aldo MAGGIONI (380 Itálie), Òscar MIRÓ (724 Španělsko), Naoki SATO (392 Japonsko), Katsuya KAJIMOTO (392 Japonsko), Alain COHEN-SOLAL (250 Francie), Enrique FAIRMAN (32 Argentina), Johan LASSUS (246 Finsko), Christian MUELLER (756 Švýcarsko), William F. PEACOCK (840 Spojené státy), James L. Jr. JANUZZI (840 Spojené státy), Dong-Ju CHOI (410 Korejská republika), Patrick PLAISANCE (250 Francie), Jindřich ŠPINAR (203 Česká republika, domácí), Alexandre MEBAZAA (250 Francie) a Etienne GAYAT (250 Francie)

Vydání

European Journal of heart Failure, Hoboken, Wiley-Blackwell, 2015, 1388-9842

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 5.135

Kód RIV

RIV/00216224:14110/15:00085125

Organizační jednotka

Lékařská fakulta

UT WoS

000366415100006

Klíčová slova anglicky

Heart failure;Heart failure with reduced ejection fraction;Elderly;Cardiac risk factors and prevention;Diabetes;Heart failure with preserved ejection fraction

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 7. 1. 2016 17:21, Soňa Böhmová

Anotace

V originále

To assess, according to age groups, patients' characteristics according to region of origin, the chronic therapeutic management, prognostic utility of clinical variables, and natriuretic peptides. Methods and results The GREAT registry consisted of patients identified as presenting with acute heart failure at the emergency department. Four groups of patients were defined according to age: the young patient group (<65 years); ‘middle-old’ (65–74 years), ‘old-old’ (75–84 years) and the ‘oldest-old’ (85–94 years). Follow-up at 1 year was performed via personal contact or national data registries at 1 year. Dataset consisted of 14 758 patients aged up to 95 years, with the ‘oldest-old’ group being more prevalent in North America and Western Europe. The 30-day mortality rate were, respectively, 8.1%, 8.9%, 10.3%, and 16.3% among the four age groups and 1-year mortality rates were, respectively, 3.1%, 17.1%, 24.7%, and 39.9%. Chronic heart failure treatment was less frequently administered with age (percentage of the ‘fully treated’ group was 14% in the ‘young’ compared with 2% in the ‘oldest-old’ patient group). Reduced left ventricular ejection fraction was present in 70%, 62.3%, 52.5%, and 46.8% among the four age groups, respectively. The prognostic utility of most variables for short- and long-term outcome was attenuated with age, with the exception of natriuretic peptides. Conclusion This study found a large heterogeneity in age among geographic regions and that the eldest are less likely to be treated in accordance with recommendations of current heart failure guidelines. Natriuretic peptide concentrations retained prognostic value in patients across age strata.