The Role of Anterior Nuclei of the Thalamus: A Subcortical Gate
in Memory Processing: An Intracerebral Recording Study

J 2015

The Role of Anterior Nuclei of the Thalamus: A Subcortical Gate in Memory Processing: An Intracerebral Recording Study

ŠTILLOVÁ, Klára, Pavel JURÁK, Jan CHLÁDEK, Jan CHRASTINA, Josef HALÁMEK et. al.

Základní údaje

Originální název

The Role of Anterior Nuclei of the Thalamus: A Subcortical Gate in Memory Processing: An Intracerebral Recording Study

Autoři

ŠTILLOVÁ, Klára (703 Slovensko, domácí), Pavel JURÁK (203 Česká republika), Jan CHLÁDEK (203 Česká republika), Jan CHRASTINA (203 Česká republika, domácí), Josef HALÁMEK (203 Česká republika), Martina BOČKOVÁ (203 Česká republika, domácí), Sabina GOLDEMUNDOVÁ (203 Česká republika, domácí), Ivo ŘÍHA (203 Česká republika, domácí) a Ivan REKTOR (203 Česká republika, garant, domácí)

Vydání

PLOS ONE, San Francisco, Public Library of Science, 2015, 1932-6203

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.057

Kód RIV

RIV/00216224:14740/15:00081297

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1371/journal.pone.0140778

UT WoS

000364032600012

Klíčová slova anglicky

ANT; anterior nuclein of the thalamus; deep brain stimulation; epilepsy

Štítky

podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 9. 3. 2017 16:08, Mgr. Eva Špillingová

Anotace

V originále

Objective To study the involvement of the anterior nuclei of the thalamus (ANT) as compared to the involvement of the hippocampus in the processes of encoding and recognition during visual and verbal memory tasks. Methods We studied intracerebral recordings in patients with pharmacoresistent epilepsy who underwent deep brain stimulation (DBS) of the ANT with depth electrodes implanted bilaterally in the ANT and compared the results with epilepsy surgery candidates with depth electrodes implanted bilaterally in the hippocampus. We recorded the event-related potentials (ERPs) elicited by the visual and verbal memory encoding and recognition tasks. Results P300-like potentials were recorded in the hippocampus by visual and verbal memory encoding and recognition tasks and in the ANT by the visual encoding and visual and verbal recognition tasks. No significant ERPs were recorded during the verbal encoding task in the ANT. In the visual and verbal recognition tasks, the P300-like potentials in the ANT preceded the P300-like potentials in the hippocampus. Conclusions The ANT is a structure in the memory pathway that processes memory information before the hippocampus. We suggest that the ANT has a specific role in memory processes, especially memory recognition, and that memory disturbance should be considered in patients with ANT-DBS and in patients with ANT lesions. ANT is well positioned to serve as a subcortical gate for memory processing in cortical structures.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

GAP103/11/0933, projekt VaV

Název: Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

Investor: Grantová agentura ČR, Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

Přiložené soubory

1320451.pdf

Požádat o autorskou verzi souboru

Citovat

ŠTILLOVÁ, Klára, Pavel JURÁK, Jan CHLÁDEK, Jan CHRASTINA, Josef HALÁMEK, Martina BOČKOVÁ, Sabina GOLDEMUNDOVÁ, Ivo ŘÍHA a Ivan REKTOR. The Role of Anterior Nuclei of the Thalamus: A Subcortical Gate in Memory Processing: An Intracerebral Recording Study. PLOS ONE. San Francisco: Public Library of Science, 2015, roč. 10, č. 11, s. nestránkováno, 13 s. ISSN 1932-6203. Dostupné z: https://dx.doi.org/10.1371/journal.pone.0140778.

@article{1320451,
   author = {Štillová, Klára and Jurák, Pavel and Chládek, Jan and Chrastina, Jan and Halámek, Josef and Bočková, Martina and Goldemundová, Sabina and Říha, Ivo and Rektor, Ivan},
   article_location = {San Francisco},
   article_number = {11},
   doi = {http://dx.doi.org/10.1371/journal.pone.0140778},
   keywords = {ANT; anterior nuclein of the thalamus; deep brain stimulation; epilepsy},
   language = {eng},
   issn = {1932-6203},
   journal = {PLOS ONE},
   title = {The Role of Anterior Nuclei of the Thalamus: A Subcortical Gate in Memory Processing: An Intracerebral Recording Study},
   url = {http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140778},
   volume = {10},
   year = {2015}
}

TY  - JOUR
ID  - 1320451
AU  - Štillová, Klára - Jurák, Pavel - Chládek, Jan - Chrastina, Jan - Halámek, Josef - Bočková, Martina - Goldemundová, Sabina - Říha, Ivo - Rektor, Ivan
PY  - 2015
TI  - The Role of Anterior Nuclei of the Thalamus: A Subcortical Gate in Memory Processing: An Intracerebral Recording Study
JF  - PLOS ONE
VL  - 10
IS  - 11
SP  - nestránkováno
EP  - nestránkováno
PB  - Public Library of Science
SN  - 19326203
KW  - ANT
KW  - anterior nuclein of the thalamus
KW  - deep brain stimulation
KW  - epilepsy
UR  - http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140778
L2  - http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140778
N2  - Objective To study the involvement of the anterior nuclei of the thalamus (ANT) as compared to the involvement of the hippocampus in the processes of encoding and recognition during visual and verbal memory tasks. Methods We studied intracerebral recordings in patients with pharmacoresistent epilepsy who underwent deep brain stimulation (DBS) of the ANT with depth electrodes implanted bilaterally in the ANT and compared the results with epilepsy surgery candidates with depth electrodes implanted bilaterally in the hippocampus. We recorded the event-related potentials (ERPs) elicited by the visual and verbal memory encoding and recognition tasks. Results P300-like potentials were recorded in the hippocampus by visual and verbal memory encoding and recognition tasks and in the ANT by the visual encoding and visual and verbal recognition tasks. No significant ERPs were recorded during the verbal encoding task in the ANT. In the visual and verbal recognition tasks, the P300-like potentials in the ANT preceded the P300-like potentials in the hippocampus. Conclusions The ANT is a structure in the memory pathway that processes memory information before the hippocampus. We suggest that the ANT has a specific role in memory processes, especially memory recognition, and that memory disturbance should be considered in patients with ANT-DBS and in patients with ANT lesions. ANT is well positioned to serve as a subcortical gate for memory processing in cortical structures.
ER  -

ŠTILLOVÁ, Klára, Pavel JURÁK, Jan CHLÁDEK, Jan CHRASTINA, Josef HALÁMEK, Martina BOČKOVÁ, Sabina GOLDEMUNDOVÁ, Ivo ŘÍHA a Ivan REKTOR. The Role of Anterior Nuclei of the Thalamus: A Subcortical Gate in Memory Processing: An Intracerebral Recording Study. \textit{PLOS ONE}. San Francisco: Public Library of Science, 2015, roč.~10, č.~11, s.~nestránkováno, 13 s. ISSN~1932-6203. Dostupné z: https://dx.doi.org/10.1371/journal.pone.0140778.

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