J 2015

Response to Letter Regarding Article, "Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: A Prospective Study From the International Collaboration on Endocarditis"

CHU, V.H., L.P. PARK, E. ATHAN, F. DELAHAYE, Tomáš FREIBERGER et. al.

Základní údaje

Originální název

Response to Letter Regarding Article, "Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: A Prospective Study From the International Collaboration on Endocarditis"

Autoři

CHU, V.H. (840 Spojené státy), L.P. PARK (840 Spojené státy), E. ATHAN (36 Austrálie), F. DELAHAYE (250 Francie), Tomáš FREIBERGER (203 Česká republika, garant, domácí), C. LAMAS (76 Brazílie), J.M. MIRO (724 Španělsko), D.W. MUDRICK (840 Spojené státy), J. STRAHILEVITZ (376 Izrael), C. TRIBOUILLOY (250 Francie), E. DURANTE-MANGONI (380 Itálie), J.M. PERICAS (724 Španělsko), N. FERNANDEZ-HIDALGO (724 Španělsko), F. NACINOVICH (32 Argentina), H. RIZK (818 Egypt), V. KRAJINOVIC (191 Chorvatsko), E. GIANNITSIOTI (300 Řecko), J.P. HURLEY (372 Irsko), M.M. HANNAN (372 Irsko) a A. WANG (840 Spojené státy)

Vydání

Circulation, Philadelphia, Lippincott Williams Wilkins, 2015, 0009-7322

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 17.202

Kód RIV

RIV/00216224:14740/15:00085138

Organizační jednotka

Středoevropský technologický institut

UT WoS

000362217300007

Klíčová slova anglicky

VALVE ENDOCARDITIS; EARLY SURGERY; MORTALITY; IMPACT

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 9. 12. 2015 07:09, Martina Prášilová

Anotace

V originále

We appreciate the thoughtful comments of Drs Almonedro-Delia, Galvez-Acebal, and Rodriguez-Bano regarding our recent publication, “Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: a Prospective Study From the International Collaboration on Endocarditis.”1 These authors raise important issues for evaluating the impact of surgery on patient outcomes, particularly survival. We strongly agree that treatment selection bias and survivor bias are major issues when evaluating the impact of surgery on mortality and that the use of appropriate statistical methodologies is necessary to quantify an unbiased and causal association of the effect of surgical treatment on outcome. In our previous studies on the impact of surgery on mortality, we have used such methods, including propensity scores,2 to account for selection bias and Cox proportional hazards models with surgery entered as a time-dependent covariate3,4 for survivor bias adjustment. However, the objective of the current study was to evaluate the differences in clinical characteristics comparing patients treated with and without cardiac surgery for infective endocarditis, and to evaluate the relationship between surgical indications, operative risk (by using the Society of Thoracic Surgeons operative risk score), and outcome. Our results emphasize the relevance of specific surgical indications in treatment decisions in infective endocarditis, and the relationship between the Society of Thoracic Surgeons operative risk score and outcome, as well. The purpose of our study was not to determine the prognostic influence of surgery in comparison with medical therapy alone in infective endocarditis.