2015
Response to Letter Regarding Article, "Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: A Prospective Study From the International Collaboration on Endocarditis"
CHU, V.H., L.P. PARK, E. ATHAN, F. DELAHAYE, Tomáš FREIBERGER et. al.Základní údaje
Originální název
Response to Letter Regarding Article, "Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: A Prospective Study From the International Collaboration on Endocarditis"
Autoři
CHU, V.H. (840 Spojené státy), L.P. PARK (840 Spojené státy), E. ATHAN (36 Austrálie), F. DELAHAYE (250 Francie), Tomáš FREIBERGER (203 Česká republika, garant, domácí), C. LAMAS (76 Brazílie), J.M. MIRO (724 Španělsko), D.W. MUDRICK (840 Spojené státy), J. STRAHILEVITZ (376 Izrael), C. TRIBOUILLOY (250 Francie), E. DURANTE-MANGONI (380 Itálie), J.M. PERICAS (724 Španělsko), N. FERNANDEZ-HIDALGO (724 Španělsko), F. NACINOVICH (32 Argentina), H. RIZK (818 Egypt), V. KRAJINOVIC (191 Chorvatsko), E. GIANNITSIOTI (300 Řecko), J.P. HURLEY (372 Irsko), M.M. HANNAN (372 Irsko) a A. WANG (840 Spojené státy)
Vydání
Circulation, Philadelphia, Lippincott Williams Wilkins, 2015, 0009-7322
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 17.202
Kód RIV
RIV/00216224:14740/15:00085138
Organizační jednotka
Středoevropský technologický institut
UT WoS
000362217300007
Klíčová slova anglicky
VALVE ENDOCARDITIS; EARLY SURGERY; MORTALITY; IMPACT
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 9. 12. 2015 07:09, Martina Prášilová
Anotace
V originále
We appreciate the thoughtful comments of Drs Almonedro-Delia, Galvez-Acebal, and Rodriguez-Bano regarding our recent publication, “Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: a Prospective Study From the International Collaboration on Endocarditis.”1 These authors raise important issues for evaluating the impact of surgery on patient outcomes, particularly survival. We strongly agree that treatment selection bias and survivor bias are major issues when evaluating the impact of surgery on mortality and that the use of appropriate statistical methodologies is necessary to quantify an unbiased and causal association of the effect of surgical treatment on outcome. In our previous studies on the impact of surgery on mortality, we have used such methods, including propensity scores,2 to account for selection bias and Cox proportional hazards models with surgery entered as a time-dependent covariate3,4 for survivor bias adjustment. However, the objective of the current study was to evaluate the differences in clinical characteristics comparing patients treated with and without cardiac surgery for infective endocarditis, and to evaluate the relationship between surgical indications, operative risk (by using the Society of Thoracic Surgeons operative risk score), and outcome. Our results emphasize the relevance of specific surgical indications in treatment decisions in infective endocarditis, and the relationship between the Society of Thoracic Surgeons operative risk score and outcome, as well. The purpose of our study was not to determine the prognostic influence of surgery in comparison with medical therapy alone in infective endocarditis.