GROSSOVÁ, L., R. JIŘÍK, Karel SOUČEK, Eva DRAŽANOVÁ and Zenon STARČUK. Comparison ASL and DCE-MRI Perfusion Map in Small Animal Model of Cancer. In Ján Maňka, Milan Tyšler, Vikor Witkovský, Ivan Frollo. Measurement 2015 : Proceedings of the 10th International Conference on Measurement. Bratislava: Institute of Measurement Science, SAS, 2015, p. 153-156. ISBN 978-80-969672-9-2.
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Basic information
Original name Comparison ASL and DCE-MRI Perfusion Map in Small Animal Model of Cancer
Authors GROSSOVÁ, L., R. JIŘÍK, Karel SOUČEK, Eva DRAŽANOVÁ and Zenon STARČUK.
Edition Bratislava, Measurement 2015 : Proceedings of the 10th International Conference on Measurement, p. 153-156, 4 pp. 2015.
Publisher Institute of Measurement Science, SAS
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW URL
Organization unit Faculty of Medicine
ISBN 978-80-969672-9-2
Keywords in English blood flow quantification; ASL; DCE-MRI; Perfusion; Tumour
Tags EL OK
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 21/1/2016 11:59.
Abstract
This paper is focused on quantitative perfusion analysis using pulsed ASL (FAIRRARE) and DCE-MRI (using high- and low-molecular-weight contrast agents) in a mouse tumour model. Tumour blood-flow maps of both methods were compared using visual assessment, region analysis (median, percentiles), scatter plots and correlation coefficients. ASL blood-flow estimates matched the DCE-MRI blood-flow estimations in some cases. Possible reasons for poor match in the other cases were investigated. This study indicates that in tumour perfusion analysis, we might profit from the combination of ASL and DCEMRI instead of using just one of them.
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