Development of causal interactions between systolic blood
pressure and inter-beat intervals in adolescents

J 2015

Development of causal interactions between systolic blood pressure and inter-beat intervals in adolescents

SVAČINOVÁ, Jana, M. JAVORKA, Zuzana NOVÁKOVÁ, Eva ZÁVODNÁ, B. CZIPPELOVÁ et. al.

Základní údaje

Originální název

Development of causal interactions between systolic blood pressure and inter-beat intervals in adolescents

Autoři

SVAČINOVÁ, Jana (203 Česká republika, garant, domácí), M. JAVORKA (703 Slovensko), Zuzana NOVÁKOVÁ (203 Česká republika, domácí), Eva ZÁVODNÁ (203 Česká republika), B. CZIPPELOVÁ (703 Slovensko) a Nataša HONZÍKOVÁ (203 Česká republika)

Vydání

Physiological Research, Praha, Fyziologický ústav AV ČR, 2015, 0862-8408

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.643

Kód RIV

RIV/00216224:14110/15:00085414

Organizační jednotka

Lékařská fakulta

UT WoS

000367547900004

Klíčová slova anglicky

Baroreflex; Causality; Conditional entropy; Autonomic nervous system; Adolescents

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 15. 2. 2020 14:55, Mgr. Vojtěch Juřík, Ph.D.

Anotace

V originále

Systolic blood pressure (SBP) changes control the cardiac inter-beat intervals (IBI) duration via baroreflex. Conversely, SBP is influenced by IBI via non-baroreflex mechanisms. Both causal pathways (feedback – baroreflex and feedforward – non-baroreflex) form a closed loop of the SBP – IBI interaction. The aim of this study was to assess the age-related changes in the IBI – SBP interaction. We have non-invasively recorded resting beat-to-beat SBP and IBI in 335 healthy subjects of different age, ranging from 11 to 23 years. Using a linear autoregressive bivariate model we obtained gain (GainSBP,IBI, used traditionally as baroreflex sensitivity) and coherence (CohSBP,IBI) of the SBP–IBI interaction and causal gain and coherence in baroreflex (GainSBP IBI, CohSBP IBI) and coherence in non-baroreflex (CohIBI SBP) directions separately. A non-linear approach was used for causal coupling indices evaluation (CSBP IBI, CIBI SBP) quantifying the amount of information transferred between signals. We performed a correlation to age analysis of all measures. CohIBI SBP and CIBI SBP were higher than CohSBP IBI and CSBP IBI, respectively. GainSBP,IBI increased and CohSBP IBI decreased with age. The coupling indices did not correlate with age. We conclude that the feedforward influence dominated at rest. The increase of GainSBP,IBI with age was not found in the closed loop model. A decrease of CohSBP IBI could be related to a change in the cardiovascular control system complexity during maturation.

Návaznosti

MUNI/A/1326/2014, interní kód MU

Název: Kardiovaskulární systém od buňky k lůžku pacienta (Akronym: KASBUNPAC)

Investor: Masarykova univerzita, Kardiovaskulární systém od buňky k lůžku pacienta, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

SVAČINOVÁ, Jana, M. JAVORKA, Zuzana NOVÁKOVÁ, Eva ZÁVODNÁ, B. CZIPPELOVÁ a Nataša HONZÍKOVÁ. Development of causal interactions between systolic blood pressure and inter-beat intervals in adolescents. Physiological Research. Praha: Fyziologický ústav AV ČR, 2015, roč. 64, č. 6, s. 821-829. ISSN 0862-8408.

@article{1322199,
   author = {Svačinová, Jana and Javorka, M. and Nováková, Zuzana and Závodná, Eva and Czippelová, B. and Honzíková, Nataša},
   article_location = {Praha},
   article_number = {6},
   keywords = {Baroreflex; Causality; Conditional entropy; Autonomic nervous system; Adolescents},
   language = {eng},
   issn = {0862-8408},
   journal = {Physiological Research},
   title = {Development of causal interactions between systolic blood pressure and inter-beat intervals in adolescents},
   volume = {64},
   year = {2015}
}

TY  - JOUR
ID  - 1322199
AU  - Svačinová, Jana - Javorka, M. - Nováková, Zuzana - Závodná, Eva - Czippelová, B. - Honzíková, Nataša
PY  - 2015
TI  - Development of causal interactions between systolic blood pressure and inter-beat intervals in adolescents
JF  - Physiological Research
VL  - 64
IS  - 6
SP  - 821-829
EP  - 821-829
PB  - Fyziologický ústav AV ČR
SN  - 08628408
KW  - Baroreflex
KW  - Causality
KW  - Conditional entropy
KW  - Autonomic nervous system
KW  - Adolescents
N2  - Systolic blood pressure (SBP) changes control the cardiac inter-beat intervals (IBI) duration via baroreflex. Conversely, SBP is influenced by IBI via non-baroreflex mechanisms. Both causal pathways (feedback – baroreflex and feedforward – non-baroreflex) form a closed loop of the SBP – IBI interaction. The aim of this study was to assess the age-related changes in the IBI – SBP interaction. We have non-invasively recorded resting beat-to-beat SBP and IBI in 335 healthy subjects of different age, ranging from 11 to 23 years. Using a linear autoregressive bivariate model we obtained gain (GainSBP,IBI, used traditionally as baroreflex sensitivity) and coherence (CohSBP,IBI) of the SBP–IBI interaction and causal gain and coherence in baroreflex (GainSBP IBI, CohSBP IBI) and coherence in non-baroreflex (CohIBI SBP) directions separately. A non-linear approach was used for causal coupling indices evaluation (CSBP IBI, CIBI SBP) quantifying the amount of information transferred between signals. We performed a correlation to age analysis of all measures. CohIBI SBP and CIBI SBP were higher than CohSBP IBI and CSBP IBI, respectively. GainSBP,IBI increased and CohSBP IBI decreased with age. The coupling indices did not correlate with age. We conclude that the feedforward influence dominated at rest. The increase of GainSBP,IBI with age was not found in the closed loop model. A decrease of CohSBP IBI could be related to a change in the cardiovascular control system complexity during maturation.
ER  -

SVAČINOVÁ, Jana, M. JAVORKA, Zuzana NOVÁKOVÁ, Eva ZÁVODNÁ, B. CZIPPELOVÁ a Nataša HONZÍKOVÁ. Development of causal interactions between systolic blood pressure and inter-beat intervals in adolescents. \textit{Physiological Research}. Praha: Fyziologický ústav AV ČR, 2015, roč.~64, č.~6, s.~821-829. ISSN~0862-8408.

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