| BARTÁKOVÁ, Vendula, Linda KLIMEŠOVÁ, Katarína KIANIČKOVÁ, Veronika DVOŘÁKOVÁ, Denisa MALÚŠKOVÁ, Jitka ŘEHOŘOVÁ, Jan SVOJANOVSKÝ, Jindřich OLŠOVSKÝ, Jana BĚLOBRÁDKOVÁ a Kateřina KAŇKOVÁ. Resting heart rate does not predict cardiovascular and renal outcomes in type 2 diabetic patients. Journal of Diabetes Research. New York: Hindawi Publishing, 2016, roč. 2016, č. 6726492, s. 1-7. ISSN 2314-6745. Dostupné z: https://dx.doi.org/10.1155/2016/6726492. |
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@article{1322360,
author = {Bartáková, Vendula and Klimešová, Linda and Kianičková, Katarína and Dvořáková, Veronika and Malúšková, Denisa and Řehořová, Jitka and Svojanovský, Jan and Olšovský, Jindřich and Bělobrádková, Jana and Kaňková, Kateřina},
article_location = {New York},
article_number = {6726492},
doi = {http://dx.doi.org/10.1155/2016/6726492},
keywords = {Diabetic kidney disease},
language = {eng},
issn = {2314-6745},
journal = {Journal of Diabetes Research},
title = {Resting heart rate does not predict cardiovascular and renal outcomes in type 2 diabetic patients},
url = {http://www.hindawi.com/journals/jdr/2016/6726492/},
volume = {2016},
year = {2016}
}
TY - JOUR
ID - 1322360
AU - Bartáková, Vendula - Klimešová, Linda - Kianičková, Katarína - Dvořáková, Veronika - Malúšková, Denisa - Řehořová, Jitka - Svojanovský, Jan - Olšovský, Jindřich - Bělobrádková, Jana - Kaňková, Kateřina
PY - 2016
TI - Resting heart rate does not predict cardiovascular and renal outcomes in type 2 diabetic patients
JF - Journal of Diabetes Research
VL - 2016
IS - 6726492
SP - 1-7
EP - 1-7
PB - Hindawi Publishing
SN - 23146745
KW - Diabetic kidney disease
UR - http://www.hindawi.com/journals/jdr/2016/6726492/
N2 - Elevated resting heart rate (RHR) has been associated with increased risk of mortality and cardiovascular events. Limited data are available so far in type 2 diabetic (T2DM) subjects with no study focusing on progressive renal decline specifically. Aims of our study were to verify RHR as a simple and reliable predictor of adverse disease outcomes in T2DM patients. A total of 421 T2DM patients with variable baseline stage of diabetic kidney disease (DKD) were prospectively followed. A history of the cardiovascular disease was present in 81 patients at baseline, DKD (glomerular filtration rate 60ml/min or proteinuria) was present in 328 at baseline. Progressive renal decline was defined as a continuous rate of glomerular filtration rate loss more than3.3% per year. Resting heart rate was not significantly higher in subjects with cardiovascular disease or DKD at baseline compared to those without. Using time-to-event analyses significant differences in the cumulative incidence of the studied outcomes, i.e. progression of DKD (and specifically progressive renal decline), major advanced cardiovascular event and all-cause mortality, between RHR 65 (arbitrary cut-off) or 75 (median) bpm were not found. We did not ascertained predictive value of the RHR for the renal or cardiovascular outcomes in T2DM subjects in the Czech Republic.
ER -
BARTÁKOVÁ, Vendula, Linda KLIMEŠOVÁ, Katarína KIANIČKOVÁ, Veronika DVOŘÁKOVÁ, Denisa MALÚŠKOVÁ, Jitka ŘEHOŘOVÁ, Jan SVOJANOVSKÝ, Jindřich OLŠOVSKÝ, Jana BĚLOBRÁDKOVÁ a Kateřina KAŇKOVÁ. Resting heart rate does not predict cardiovascular and renal outcomes in type 2 diabetic patients. \textit{Journal of Diabetes Research}. New York: Hindawi Publishing, 2016, roč.~2016, č.~6726492, s.~1-7. ISSN~2314-6745. Dostupné z: https://dx.doi.org/10.1155/2016/6726492.
|
