Další formáty:
BibTeX
LaTeX
RIS
@article{1322637,
author = {Paleček, Jan and Gruber, Stephan},
article_location = {CAMBRIDGE},
article_number = {12},
doi = {http://dx.doi.org/10.1016/j.str.2015.10.004},
keywords = {SMC structural maintenance of chromosomes; Cohesin; Condensin; Smc5/6; MukBEF; MksBEF; MAGE; Smc/ScpAB; kleisin; chromosome segregation; cohesion; condensation; replication; winged helix domains; kite proteins},
language = {eng},
issn = {0969-2126},
journal = {Structure},
title = {Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes},
url = {http://www.sciencedirect.com/science/article/pii/S0969212615004128},
volume = {23},
year = {2015}
}
TY - JOUR
ID - 1322637
AU - Paleček, Jan - Gruber, Stephan
PY - 2015
TI - Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes
JF - Structure
VL - 23
IS - 12
SP - 2183-2190
EP - 2183-2190
PB - CELL PRESS
SN - 09692126
KW - SMC structural maintenance of chromosomes
KW - Cohesin
KW - Condensin
KW - Smc5/6
KW - MukBEF
KW - MksBEF
KW - MAGE
KW - Smc/ScpAB
KW - kleisin
KW - chromosome segregation
KW - cohesion
KW - condensation
KW - replication
KW - winged helix domains
KW - kite proteins
UR - http://www.sciencedirect.com/science/article/pii/S0969212615004128
L2 - http://www.sciencedirect.com/science/article/pii/S0969212615004128
N2 - SMC/kleisin complexes form elongated annular structures, which are critical for chromosome segregation, genome maintenance, and the regulation of gene expression. We describe marked structural similarities between bacterial and eukaryotic SMC/kleisin partner proteins (designated here as "kite'' proteins for kleisin interacting tandem winged-helix (WH) elements of SMC complexes). Kite proteins are integral parts of all prokaryotic SMC complexes and Smc5/6 but not cohesin and condensin. They are made up of tandem WH domains, form homo-or heterodimers via their amino-terminal WH domain, and they associate with the central part of a kleisin subunit. In placental mammals, the kite subunit NSE3 gave rise to several (>60) kite-related proteins, named MAGE, many of which encode tumor-and testis-specific antigens. Based on architectural rather than sequence similarity, we propose an adapted model for the evolution of the SMC protein complexes and discuss potential functional similarities between bacterial Smc/ScpAB and eukaryotic Smc5/6.
ER -
PALEČEK, Jan a Stephan GRUBER. Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes. \textit{Structure}. CAMBRIDGE: CELL PRESS, 2015, roč.~23, č.~12, s.~2183-2190. ISSN~0969-2126. Dostupné z: https://dx.doi.org/10.1016/j.str.2015.10.004.
|
