Automated Tube Voltage Selection for Radiation Dose Reduction
in CT Angiography Using Different Contrast Media Concentrations
and a Constant Iodine Delivery Rate

J 2015

Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate

KOK, Madeleine, Casper MIHL, Anna SEEHOFNEROVÁ, Jakub TUREK, Gregor JOST et. al.

Základní údaje

Originální název

Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate

Autoři

KOK, Madeleine (528 Nizozemské království), Casper MIHL (528 Nizozemské království), Anna SEEHOFNEROVÁ (203 Česká republika, domácí), Jakub TUREK (703 Slovensko, garant, domácí), Gregor JOST (276 Německo), Hubertus PIETSCH (276 Německo), Ulrike HABERLAND (276 Německo), Joachim E. WILDBERGER (528 Nizozemské království) a Marco DAS (528 Nizozemské království)

Vydání

American Journal of Roentgenology, Reston, American Roentgen Ray Society, 2015, 0361-803X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.660

Kód RIV

RIV/00216224:14110/15:00086075

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.2214/AJR.14.13957

UT WoS

000365320400039

Klíčová slova anglicky

automated tube potential selection; contrast media; CT angiography; radiation exposure

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 1. 2016 16:58, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

OBJECTIVE. The purpose of this study was to systematically investigate radiation dose reduction using automated tube voltage selection during CT angiography (CTA) and to evaluate the impact of contrast medium (CM) injection protocols on dose reduction. MATERIALS AND METHODS. A circulation phantom containing the thoracic and abdominal vasculature was used. Four different concentrations of CM (iopromide 300 and 370 mg I/mL and iomeprol 350 and 400 mg I/mL) were administered while maintaining an identical iodine delivery rate (1.8 g I/s) and total iodine load (20.0 g). Three different scanning protocols for CTA of the thoracoabdominal aorta were used: protocol A, no dose modulation; protocol B, automated tube current modulation (CARE Dose4D); and protocol C, automated tube voltage selection (CARE kV). The dose-length product was recorded to calculate the effective dose. Attenuation values (in Hounsfield units), image noise levels, and signal-to-noise ratios (SNRs) in six predefined intravascular sites (three thoracic and three abdominal) were measured by two readers. All values were analyzed using the Kruskal-Wallis test and two-way ANOVA. RESULTS. There was a significant reduction in the effective dose (in millisieverts) for protocols B (mean +/- SD, 2.03 +/- 0.1 mSv) and C (1.00 +/- 0.0 mSv) compared with protocol A (4.34 +/- 0.0 mSv). The dose was reduced by 53% for protocol B and by 77% for protocol C. No significant differences were found in the effective dose among the different CM injection protocols within the scanning protocols; all p values were > 0.05. The attenuation values and SNRs were comparable among all the different CM injection protocols; all p values were > 0.05. CONCLUSION. A large radiation dose reduction (77%) can be achieved using automated tube voltage selection independent of the CM injection protocol.

Citovat

KOK, Madeleine, Casper MIHL, Anna SEEHOFNEROVÁ, Jakub TUREK, Gregor JOST, Hubertus PIETSCH, Ulrike HABERLAND, Joachim E. WILDBERGER a Marco DAS. Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate. American Journal of Roentgenology. Reston: American Roentgen Ray Society, 2015, roč. 205, č. 6, s. 1332-1338. ISSN 0361-803X. Dostupné z: https://dx.doi.org/10.2214/AJR.14.13957.

@article{1331465,
   author = {Kok, Madeleine and Mihl, Casper and Seehofnerová, Anna and Turek, Jakub and Jost, Gregor and Pietsch, Hubertus and Haberland, Ulrike and Wildberger, Joachim E. and Das, Marco},
   article_location = {Reston},
   article_number = {6},
   doi = {http://dx.doi.org/10.2214/AJR.14.13957},
   keywords = {automated tube potential selection; contrast media; CT angiography; radiation exposure},
   language = {eng},
   issn = {0361-803X},
   journal = {American Journal of Roentgenology},
   title = {Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate},
   volume = {205},
   year = {2015}
}

TY  - JOUR
ID  - 1331465
AU  - Kok, Madeleine - Mihl, Casper - Seehofnerová, Anna - Turek, Jakub - Jost, Gregor - Pietsch, Hubertus - Haberland, Ulrike - Wildberger, Joachim E. - Das, Marco
PY  - 2015
TI  - Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate
JF  - American Journal of Roentgenology
VL  - 205
IS  - 6
SP  - 1332-1338
EP  - 1332-1338
PB  - American Roentgen Ray Society
SN  - 0361803X
KW  - automated tube potential selection
KW  - contrast media
KW  - CT angiography
KW  - radiation exposure
N2  - OBJECTIVE. The purpose of this study was to systematically investigate radiation dose reduction using automated tube voltage selection during CT angiography (CTA) and to evaluate the impact of contrast medium (CM) injection protocols on dose reduction. MATERIALS AND METHODS. A circulation phantom containing the thoracic and abdominal vasculature was used. Four different concentrations of CM (iopromide 300 and 370 mg I/mL and iomeprol 350 and 400 mg I/mL) were administered while maintaining an identical iodine delivery rate (1.8 g I/s) and total iodine load (20.0 g). Three different scanning protocols for CTA of the thoracoabdominal aorta were used: protocol A, no dose modulation; protocol B, automated tube current modulation (CARE Dose4D); and protocol C, automated tube voltage selection (CARE kV). The dose-length product was recorded to calculate the effective dose. Attenuation values (in Hounsfield units), image noise levels, and signal-to-noise ratios (SNRs) in six predefined intravascular sites (three thoracic and three abdominal) were measured by two readers. All values were analyzed using the Kruskal-Wallis test and two-way ANOVA. RESULTS. There was a significant reduction in the effective dose (in millisieverts) for protocols B (mean +/- SD, 2.03 +/- 0.1 mSv) and C (1.00 +/- 0.0 mSv) compared with protocol A (4.34 +/- 0.0 mSv). The dose was reduced by 53% for protocol B and by 77% for protocol C. No significant differences were found in the effective dose among the different CM injection protocols within the scanning protocols; all p values were > 0.05. The attenuation values and SNRs were comparable among all the different CM injection protocols; all p values were > 0.05. CONCLUSION. A large radiation dose reduction (77%) can be achieved using automated tube voltage selection independent of the CM injection protocol.
ER  -

KOK, Madeleine, Casper MIHL, Anna SEEHOFNEROVÁ, Jakub TUREK, Gregor JOST, Hubertus PIETSCH, Ulrike HABERLAND, Joachim E. WILDBERGER a Marco DAS. Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate. \textit{American Journal of Roentgenology}. Reston: American Roentgen Ray Society, 2015, roč.~205, č.~6, s.~1332-1338. ISSN~0361-803X. Dostupné z: https://dx.doi.org/10.2214/AJR.14.13957.

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