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@proceedings{1335076, author = {Švachová, Veronika and Pavliňák, David and Vojtová, Lucy and Alberti, Milan and Jančář, Josef and Hyršl, Pavel}, keywords = {Elektrostatic spinning; oxidized cellulose; gelatine; baktericidal impact}, language = {eng}, isbn = {978-80-210-7159-9}, title = {Gelatin Nanofibers Modified with Oxidized Cellulose with Significant Bactericidal Effects}, year = {2014} }
TY - CONF ID - 1335076 AU - Švachová, Veronika - Pavliňák, David - Vojtová, Lucy - Alberti, Milan - Jančář, Josef - Hyršl, Pavel PY - 2014 TI - Gelatin Nanofibers Modified with Oxidized Cellulose with Significant Bactericidal Effects SN - 9788021071599 KW - Elektrostatic spinning KW - oxidized cellulose KW - gelatine KW - baktericidal impact N2 - This work is focused on the preparation of gelatin nanofibers modified with salts of oxidized cellulose. Gelatin is a biocompatible, biodegradable protein-based material with high absorption capacity, which is obtained by partial hydrolysis of natural protein - collagen. Oxidized cellulose and its salts are biocompatible as well, biodegradable and they have antibacterial and hemostatic effects. Electrospun novel nanofibers, combining properties of both gelatin and oxycellulose exhibited unique bactericide efficiency. Chemical composition of the fibers was studied by ATR-FTIR spectroscopy and EDX elemental analysis. Obtained results confirmed the presence of oxidized cellulose salt in prepared nanofibers. Diameter and morphology of nanofibers were determined by scanning electron microscopy (SEM). Bactericidal effect was examined by the method of chemical bioluminescence on modified bacterial strain of E. coli. This method proved complete mortality of E. coli in most of cases. Newly prepared material may have a potential application in surgery, regenerative medicine of soft tissue (burns) and in tissue engineering. ER -
ŠVACHOVÁ, Veronika, David PAVLIŇÁK, Lucy VOJTOVÁ, Milan ALBERTI, Josef JANČÁŘ a Pavel HYRŠL. \textit{Gelatin Nanofibers Modified with Oxidized Cellulose with Significant Bactericidal Effects}. 2014. ISBN~978-80-210-7159-9.
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