Effect of arsenic and cyanobacterial co-exposure on
pathological, haematological and immunological parameters of
rainbow trout (Oncorhynchus mykiss)

J 2015

Effect of arsenic and cyanobacterial co-exposure on pathological, haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)

PALÍKOVÁ, Miroslava, Ivana PAPEŽÍKOVÁ, Radovan KOPP, Jan MAREŠ, Zdena MARKOVÁ et. al.

Základní údaje

Originální název

Effect of arsenic and cyanobacterial co-exposure on pathological, haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)

Autoři

PALÍKOVÁ, Miroslava (203 Česká republika, garant), Ivana PAPEŽÍKOVÁ (203 Česká republika), Radovan KOPP (203 Česká republika), Jan MAREŠ (203 Česká republika), Zdena MARKOVÁ (203 Česká republika), Stanislav NAVRÁTIL (203 Česká republika), Ondřej ADAMOVSKÝ (203 Česká republika, domácí), Jiří KOHOUTEK (203 Česká republika, domácí), Lukáš NAVRÁTIL (203 Česká republika) a Luděk BLÁHA (203 Česká republika, domácí)

Vydání

Neuroendocrinology Letters, STOCKHOLM (SWEDEN), MAGHIRA & MAAS PUBLICATIONS, 2015, 0172-780X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

40103 Fishery

Stát vydavatele

Švédsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 0.946

Kód RIV

RIV/00216224:14310/15:00086973

Organizační jednotka

Přírodovědecká fakulta

UT WoS

000369404400008

Klíčová slova anglicky

microcystin; multiple exposure; lymphocytosis; neutropenia; phagocytic activity; fish

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 5. 2017 15:56, Ing. Nicole Zrilić

Anotace

V originále

OBJECTIVES: Under environmental conditions, fish are simultaneously exposed to multiple stressors. This study provides new knowledge on the effects of controlled exposure to multiple stressors, namely cyanobacterial biomass and food contaminated with arsenic. METHODS: Rainbow trout were divided into six groups of 25 fish and exposed to different contaminant combinations for 30 days: 1) control group, 2) cyanobacterial biomass, 3 & 4) two groups exposed to arsenic at concentrations of 5 mg.kg(-1) and 50 mg.kg(-1) fish feed, and 5 & 6) two groups exposed to cyanobacterial biomass and arsenic combined. We then evaluated pathological, haematological and immunological parameters at 10, 20 and 30 days after exposure. RESULTS: Marked gross pathological findings were present in groups exposed to arsenic and arsenic/cyanobacteria after 30 days. A strong decrease in haemoglobin concentration was observed in all experimental groups receiving arsenic after 10 days exposure. Total leukocyte count increased markedly in fish exposed to cyanobacterial biomass, and to higher arsenic concentrations by the end of the experiment. Neutrophils decreased significantly at the end of exposure. Similarly, exposure to cyanobacteria and/or arsenic led to suppression of opsonised zymosan particle-induced neutrophil respiratory bursts. CONCLUSIONS: Our results demonstrate that the effects of exposure to toxic cyanobacterial biomass and arsenic on fish are enhanced when the contaminants are combined. In particular, long-term exposure led to disturbances in the white blood-cell count. Modulation of phagocytosis, which is the first line of defence against invading pathogens, suggests that the combined action leads to a decreased ability to control infection.

Návaznosti

LO1214, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Centrum pro výzkum toxických látek v prostředí

Citovat

PALÍKOVÁ, Miroslava, Ivana PAPEŽÍKOVÁ, Radovan KOPP, Jan MAREŠ, Zdena MARKOVÁ, Stanislav NAVRÁTIL, Ondřej ADAMOVSKÝ, Jiří KOHOUTEK, Lukáš NAVRÁTIL a Luděk BLÁHA. Effect of arsenic and cyanobacterial co-exposure on pathological, haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss). Neuroendocrinology Letters. STOCKHOLM (SWEDEN): MAGHIRA & MAAS PUBLICATIONS, 2015, roč. 36, Suppl.1, s. 57-63. ISSN 0172-780X.

@article{1338883,
   author = {Palíková, Miroslava and Papežíková, Ivana and Kopp, Radovan and Mareš, Jan and Marková, Zdena and Navrátil, Stanislav and Adamovský, Ondřej and Kohoutek, Jiří and Navrátil, Lukáš and Bláha, Luděk},
   article_location = {STOCKHOLM (SWEDEN)},
   article_number = {Suppl.1},
   keywords = {microcystin; multiple exposure; lymphocytosis; neutropenia; phagocytic activity; fish},
   language = {eng},
   issn = {0172-780X},
   journal = {Neuroendocrinology Letters},
   note = {Opraven obor publikace},
   title = {Effect of arsenic and cyanobacterial co-exposure on pathological, haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)},
   url = {http://www.ncbi.nlm.nih.gov/pubmed/26757114},
   volume = {36},
   year = {2015}
}

TY  - JOUR
ID  - 1338883
AU  - Palíková, Miroslava - Papežíková, Ivana - Kopp, Radovan - Mareš, Jan - Marková, Zdena - Navrátil, Stanislav - Adamovský, Ondřej - Kohoutek, Jiří - Navrátil, Lukáš - Bláha, Luděk
PY  - 2015
TI  - Effect of arsenic and cyanobacterial co-exposure on pathological, haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss)
JF  - Neuroendocrinology Letters
VL  - 36
IS  - Suppl.1
SP  - 57-63
EP  - 57-63
PB  - MAGHIRA & MAAS PUBLICATIONS
SN  - 0172780X
N1  - Opraven obor publikace
KW  - microcystin
KW  - multiple exposure
KW  - lymphocytosis
KW  - neutropenia
KW  - phagocytic activity
KW  - fish
UR  - http://www.ncbi.nlm.nih.gov/pubmed/26757114
L2  - http://www.ncbi.nlm.nih.gov/pubmed/26757114
N2  - OBJECTIVES: Under environmental conditions, fish are simultaneously exposed to multiple stressors. This study provides new knowledge on the effects of controlled exposure to multiple stressors, namely cyanobacterial biomass and food contaminated with arsenic. METHODS: Rainbow trout were divided into six groups of 25 fish and exposed to different contaminant combinations for 30 days: 1) control group, 2) cyanobacterial biomass, 3 & 4) two groups exposed to arsenic at concentrations of 5 mg.kg(-1) and 50 mg.kg(-1) fish feed, and 5 & 6) two groups exposed to cyanobacterial biomass and arsenic combined. We then evaluated pathological, haematological and immunological parameters at 10, 20 and 30 days after exposure. RESULTS: Marked gross pathological findings were present in groups exposed to arsenic and arsenic/cyanobacteria after 30 days. A strong decrease in haemoglobin concentration was observed in all experimental groups receiving arsenic after 10 days exposure. Total leukocyte count increased markedly in fish exposed to cyanobacterial biomass, and to higher arsenic concentrations by the end of the experiment. Neutrophils decreased significantly at the end of exposure. Similarly, exposure to cyanobacteria and/or arsenic led to suppression of opsonised zymosan particle-induced neutrophil respiratory bursts. CONCLUSIONS: Our results demonstrate that the effects of exposure to toxic cyanobacterial biomass and arsenic on fish are enhanced when the contaminants are combined. In particular, long-term exposure led to disturbances in the white blood-cell count. Modulation of phagocytosis, which is the first line of defence against invading pathogens, suggests that the combined action leads to a decreased ability to control infection.
ER  -

PALÍKOVÁ, Miroslava, Ivana PAPEŽÍKOVÁ, Radovan KOPP, Jan MAREŠ, Zdena MARKOVÁ, Stanislav NAVRÁTIL, Ondřej ADAMOVSKÝ, Jiří KOHOUTEK, Lukáš NAVRÁTIL a Luděk BLÁHA. Effect of arsenic and cyanobacterial co-exposure on pathological, haematological and immunological parameters of rainbow trout (Oncorhynchus mykiss). \textit{Neuroendocrinology Letters}. STOCKHOLM (SWEDEN): MAGHIRA \&{} MAAS PUBLICATIONS, 2015, roč.~36, Suppl.1, s.~57-63. ISSN~0172-780X.

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