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@article{1339582,
author = {Della Torre, Camilla and Buonocore, Francesco and Frenzilli, Giada and Corsolini, Simonetta and Brunelli, Andrea and Guidi, Patrizia and Kočan, Anton and Mariottini, Michela and Mottola, Filomena and Nigro, Marco and Pozo, Karla Andrea and Randelli, Elisa and Vannuccini, Maria Luisa and Picchietti, Simona and Santonastaso, Marianna and Scarcelli, Vittoria and Focardi, Silvano and Marcomini, Antonio and Rocco, Lucia and Scapigliati, Giuseppe and Corsi, Ilaria},
article_location = {OXFORD (ENGLAND)},
article_number = {JANUARY},
doi = {http://dx.doi.org/10.1016/j.envpol.2014.09.020},
keywords = {Nano-TiO2 2 3 7 8-TCDD; CYP1A; Immunomodulation; Genotoxicity},
language = {eng},
issn = {0269-7491},
journal = {Environmental Pollution},
title = {Influence of titanium dioxide nanoparticles on 2,3,7,8-tetrachlorodibenzo-p-dioxin bioconcentration and toxicity in the marine fish European sea bass (Dicentrarchus labrax)},
url = {http://www.sciencedirect.com/science/article/pii/S0269749114004254},
volume = {196},
year = {2015}
}
TY - JOUR
ID - 1339582
AU - Della Torre, Camilla - Buonocore, Francesco - Frenzilli, Giada - Corsolini, Simonetta - Brunelli, Andrea - Guidi, Patrizia - Kočan, Anton - Mariottini, Michela - Mottola, Filomena - Nigro, Marco - Pozo, Karla Andrea - Randelli, Elisa - Vannuccini, Maria Luisa - Picchietti, Simona - Santonastaso, Marianna - Scarcelli, Vittoria - Focardi, Silvano - Marcomini, Antonio - Rocco, Lucia - Scapigliati, Giuseppe - Corsi, Ilaria
PY - 2015
TI - Influence of titanium dioxide nanoparticles on 2,3,7,8-tetrachlorodibenzo-p-dioxin bioconcentration and toxicity in the marine fish European sea bass (Dicentrarchus labrax)
JF - Environmental Pollution
VL - 196
IS - JANUARY
SP - 185-193
EP - 185-193
PB - Elsevier Science
SN - 02697491
KW - Nano-TiO2 2 3 7 8-TCDD
KW - CYP1A
KW - Immunomodulation
KW - Genotoxicity
UR - http://www.sciencedirect.com/science/article/pii/S0269749114004254
L2 - http://www.sciencedirect.com/science/article/pii/S0269749114004254
N2 - The present study investigated the influence of nano-TiO2 (1 mg L-1) on 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) (46 pg L-1) bioconcentration and toxicity in the European sea bass (Dicentrarchus labrax) during 7 days in vivo exposure. A multimarkers approach was applied in different organs: detoxification in liver; innate immunity and pro-inflammatory response and adaptive immunity in gills and spleen; genotoxicity in peripheral erythrocytes and muscle. Bioconcentration of 2,3,7,8-TCDD in presence of nano-TiO2 was investigated in liver, skin and muscle as well as interaction between nanoTiO(2) and organic pollutants in artificial sea water (ASW). Nano-TiO2 negatively influenced immune response induced by 2,3,7,8-TCDD in spleen but not in gills and reduced the DNA damage induced by 2,3,7,8-TCDD in erythrocytes. nano-TiO2 did not interfere with 2,3,7,8-TCDD detoxification and bioconcentration according to the observed no interaction of the nano-TiO2 with organic pollutants in ASW.
ER -
DELLA TORRE, Camilla, Francesco BUONOCORE, Giada FRENZILLI, Simonetta CORSOLINI, Andrea BRUNELLI, Patrizia GUIDI, Anton KOČAN, Michela MARIOTTINI, Filomena MOTTOLA, Marco NIGRO, Karla Andrea POZO, Elisa RANDELLI, Maria Luisa VANNUCCINI, Simona PICCHIETTI, Marianna SANTONASTASO, Vittoria SCARCELLI, Silvano FOCARDI, Antonio MARCOMINI, Lucia ROCCO, Giuseppe SCAPIGLIATI a Ilaria CORSI. Influence of titanium dioxide nanoparticles on 2,3,7,8-tetrachlorodibenzo-p-dioxin bioconcentration and toxicity in the marine fish European sea bass (Dicentrarchus labrax). \textit{Environmental Pollution}. OXFORD (ENGLAND): Elsevier Science, 2015, roč.~196, JANUARY, s.~185-193. ISSN~0269-7491. Dostupné z: https://dx.doi.org/10.1016/j.envpol.2014.09.020.
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