ABDEL-RAHMAN, Rasha M., A. M. ABDEL-MOHSEN, Radim HRDINA, Ladislav BURGERT, Zdenka FOHLEROVÁ, David PAVLIŇÁK, O.N. SAYED and Josef JANČÁŘ. Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics: Preparation, Characterization and Medical Applications. International Journal of Biological Macromolecules. Elsevier, 2016, vol. 89, August, p. 725-736. ISSN 0141-8130. Available from: https://dx.doi.org/10.1016/j.ijbiomac.2016.04.087.
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Basic information
Original name Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics: Preparation, Characterization and Medical Applications
Authors ABDEL-RAHMAN, Rasha M. (818 Egypt, guarantor), A. M. ABDEL-MOHSEN (818 Egypt), Radim HRDINA (203 Czech Republic), Ladislav BURGERT (203 Czech Republic), Zdenka FOHLEROVÁ (203 Czech Republic), David PAVLIŇÁK (203 Czech Republic, belonging to the institution), O.N. SAYED (818 Egypt) and Josef JANČÁŘ (203 Czech Republic).
Edition International Journal of Biological Macromolecules, Elsevier, 2016, 0141-8130.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10305 Fluids and plasma physics
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW odkaz na článek
Impact factor Impact factor: 3.671
RIV identification code RIV/00216224:14310/16:00089952
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1016/j.ijbiomac.2016.04.087
UT WoS 000378951400086
Keywords in English Hyaluronan;chitosan;nonwoven fabrics;cytotoxicity;healing properties
Tags AKR, rivok
Tags International impact, Reviewed
Changed by Changed by: Ing. Andrea Mikešková, učo 137293. Changed: 26/4/2017 21:25.
Abstract
Thin layers of chitosan (positively charged)/ sodium hyaluronate (negatively charged)/ nonwoven fabrics were constructed by polyelectrolyte multilayer pad-dry-cure technique. Pure chitosan (CS) was isolated from shrimp shell and immobilized onto nonwoven fabrics (NWFs) using citric acid (CTA) as cross linker and solvent agents through a pad-dry-cure method. The prepared thin layer of chitosan citrate/ nonwoven fabrics (CSCTA/NWFs) were consequently impregnated with hyaluronan (CSCTA/HA/NWFs) in the second path through a pad-dry-cure method. Chitosan/hyaluronan/nonwoven fabrics wound dressing was characterized by different tools such as FTIR-ATR, TGA and SEM. The antibacterial activity and the cytotoxicity of the dressing sheets were evaluated against Escherichia coli (E.coli) and Streptococcus aureus (St. aureus), mouse fibroblast (NIH-3T3) and keratinocytes (HaCaT) cell lines, respectively. The cell-fabrics 4 interaction was also investigated using fluorescence microscope, based on live/dead staining assay of 3T3 cells. The healing properties of the new wound dressing were evaluated and compared with the control sample.
Links
ED2.1.00/03.0086, research and development projectName: Regionální VaV centrum pro nízkonákladové plazmové a nanotechnologické povrchové úpravy
LO1411, research and development projectName: Rozvoj centra pro nízkonákladové plazmové a nanotechnologické povrchové úpravy (Acronym: CEPLANT plus)
Investor: Ministry of Education, Youth and Sports of the CR
PrintDisplayed: 26/4/2024 20:41