Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics:
Preparation, Characterization and Medical Applications

J 2016

Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics: Preparation, Characterization and Medical Applications

ABDEL-RAHMAN, Rasha M., A. M. ABDEL-MOHSEN, Radim HRDINA, Ladislav BURGERT, Zdenka FOHLEROVÁ et. al.

Základní údaje

Originální název

Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics: Preparation, Characterization and Medical Applications

Autoři

ABDEL-RAHMAN, Rasha M. (818 Egypt, garant), A. M. ABDEL-MOHSEN (818 Egypt), Radim HRDINA (203 Česká republika), Ladislav BURGERT (203 Česká republika), Zdenka FOHLEROVÁ (203 Česká republika), David PAVLIŇÁK (203 Česká republika, domácí), O.N. SAYED (818 Egypt) a Josef JANČÁŘ (203 Česká republika)

Vydání

International Journal of Biological Macromolecules, Elsevier, 2016, 0141-8130

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10305 Fluids and plasma physics

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

odkaz na článek

Impakt faktor

Impact factor: 3.671

Kód RIV

RIV/00216224:14310/16:00089952

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.ijbiomac.2016.04.087

UT WoS

000378951400086

Klíčová slova anglicky

Hyaluronan;chitosan;nonwoven fabrics;cytotoxicity;healing properties

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 4. 2017 21:25, Ing. Andrea Mikešková

Anotace

V originále

Thin layers of chitosan (positively charged)/ sodium hyaluronate (negatively charged)/ nonwoven fabrics were constructed by polyelectrolyte multilayer pad-dry-cure technique. Pure chitosan (CS) was isolated from shrimp shell and immobilized onto nonwoven fabrics (NWFs) using citric acid (CTA) as cross linker and solvent agents through a pad-dry-cure method. The prepared thin layer of chitosan citrate/ nonwoven fabrics (CSCTA/NWFs) were consequently impregnated with hyaluronan (CSCTA/HA/NWFs) in the second path through a pad-dry-cure method. Chitosan/hyaluronan/nonwoven fabrics wound dressing was characterized by different tools such as FTIR-ATR, TGA and SEM. The antibacterial activity and the cytotoxicity of the dressing sheets were evaluated against Escherichia coli (E.coli) and Streptococcus aureus (St. aureus), mouse fibroblast (NIH-3T3) and keratinocytes (HaCaT) cell lines, respectively. The cell-fabrics 4 interaction was also investigated using fluorescence microscope, based on live/dead staining assay of 3T3 cells. The healing properties of the new wound dressing were evaluated and compared with the control sample.

Návaznosti

ED2.1.00/03.0086, projekt VaV

Název: Regionální VaV centrum pro nízkonákladové plazmové a nanotechnologické povrchové úpravy

LO1411, projekt VaV

Název: Rozvoj centra pro nízkonákladové plazmové a nanotechnologické povrchové úpravy (Akronym: CEPLANT plus)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Rozvoj centra pro nízkonákladové plazmové a nanotechnologické povrchové úpravy

Citovat

ABDEL-RAHMAN, Rasha M., A. M. ABDEL-MOHSEN, Radim HRDINA, Ladislav BURGERT, Zdenka FOHLEROVÁ, David PAVLIŇÁK, O.N. SAYED a Josef JANČÁŘ. Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics: Preparation, Characterization and Medical Applications. International Journal of Biological Macromolecules. Elsevier, 2016, roč. 89, August, s. 725-736. ISSN 0141-8130. Dostupné z: https://dx.doi.org/10.1016/j.ijbiomac.2016.04.087.

@article{1345393,
   author = {AbdelandRahman, Rasha M. and AbdelandMohsen, A. M. and Hrdina, Radim and Burgert, Ladislav and Fohlerová, Zdenka and Pavliňák, David and Sayed, O.N. and Jančář, Josef},
   article_number = {August},
   doi = {http://dx.doi.org/10.1016/j.ijbiomac.2016.04.087},
   keywords = {Hyaluronan;chitosan;nonwoven fabrics;cytotoxicity;healing properties},
   language = {eng},
   issn = {0141-8130},
   journal = {International Journal of Biological Macromolecules},
   title = {Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics: Preparation, Characterization and Medical Applications},
   url = {http://www.sciencedirect.com/science/article/pii/S0141813016304044},
   volume = {89},
   year = {2016}
}

TY  - JOUR
ID  - 1345393
AU  - Abdel-Rahman, Rasha M. - Abdel-Mohsen, A. M. - Hrdina, Radim - Burgert, Ladislav - Fohlerová, Zdenka - Pavliňák, David - Sayed, O.N. - Jančář, Josef
PY  - 2016
TI  - Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics: Preparation, Characterization and Medical Applications
JF  - International Journal of Biological Macromolecules
VL  - 89
IS  - August
SP  - 725-736
EP  - 725-736
PB  - Elsevier
SN  - 01418130
KW  - Hyaluronan;chitosan;nonwoven fabrics;cytotoxicity;healing properties
UR  - http://www.sciencedirect.com/science/article/pii/S0141813016304044
L2  - http://www.sciencedirect.com/science/article/pii/S0141813016304044
N2  - Thin layers of chitosan (positively charged)/ sodium hyaluronate (negatively charged)/ nonwoven fabrics were constructed by polyelectrolyte multilayer pad-dry-cure technique. Pure chitosan (CS) was isolated from shrimp shell and immobilized onto nonwoven fabrics (NWFs) using citric acid (CTA) as cross linker and solvent agents through a pad-dry-cure method. The prepared thin layer of chitosan citrate/ nonwoven fabrics (CSCTA/NWFs) were consequently impregnated with hyaluronan (CSCTA/HA/NWFs) in the second path through a pad-dry-cure method. Chitosan/hyaluronan/nonwoven fabrics wound dressing was characterized by different tools such as FTIR-ATR, TGA and SEM. The antibacterial activity and the cytotoxicity of the dressing sheets were evaluated against Escherichia coli (E.coli) and Streptococcus aureus (St. aureus), mouse fibroblast (NIH-3T3) and keratinocytes (HaCaT) cell lines, respectively. The cell-fabrics 4 interaction was also investigated using fluorescence microscope, based on live/dead staining assay of 3T3 cells. The healing properties of the new wound dressing were evaluated and compared with the control sample.
ER  -

ABDEL-RAHMAN, Rasha M., A. M. ABDEL-MOHSEN, Radim HRDINA, Ladislav BURGERT, Zdenka FOHLEROVÁ, David PAVLIŇÁK, O.N. SAYED a Josef JANČÁŘ. Wound Dressing based on Chitosan/hyaluronan/Nonwoven Fabrics: Preparation, Characterization and Medical Applications. \textit{International Journal of Biological Macromolecules}. Elsevier, 2016, roč.~89, August, s.~725-736. ISSN~0141-8130. Dostupné z: https://dx.doi.org/10.1016/j.ijbiomac.2016.04.087.

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