J 2016

Changes with Age in the Time Structure of Blood Pressure

CORNELISSEN, Germaine, Jarmila SIEGELOVÁ, Alena HAVELKOVÁ, Leona DUNKLEROVÁ, Jiří DUŠEK et. al.

Základní údaje

Originální název

Changes with Age in the Time Structure of Blood Pressure

Autoři

CORNELISSEN, Germaine (840 Spojené státy), Jarmila SIEGELOVÁ (203 Česká republika, garant, domácí), Alena HAVELKOVÁ (203 Česká republika, domácí), Leona DUNKLEROVÁ (203 Česká republika, domácí) a Jiří DUŠEK (203 Česká republika)

Vydání

World Heart Journal, New York, Nova Science Publishers Inc, 2016, 1556-4002

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/16:00090619

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Aging; Blood pressure; Circadian; Heart rate; Infradian; Ultradian; Variance transposition

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 24. 8. 2016 12:44, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

To map changes in the time structure of blood pressure as a function of age, we analyze 7-day/24-hour records obtained by ambulatory blood pressure monitoring. From January 2000 to June 2011, 297 records were obtained (78 from women and 219 from men). Subjects were 20 to 84 years of age. They resided in Brno, Czech Republic, and were mostly clinically healthy at the time of monitoring. All but 23 records covered a week. Data from the 274 complete records were analyzed by least squares spectrum in the frequency range from 1 cycle per week to 12 cycles per day. Population-mean cosinor spectra were obtained to assess the infradian-to-circadian (frequencies of 1 to 7 cycles per week) and circadian-to-ultradian (frequencies between 1 and 7 cycles per day) spectral domains. With increasing age, the circadian amplitude of blood pressure was reduced and the circadian acrophase of blood pressure was advanced. There was also a transposition of the variance from the circadian to both the infradian and ultradian domains. These results are in keeping with a previous investigation of a less homogeneous population. They provide further evidence for the need to refine reference standards by accounting for changes with age in circadian (and other) rhythm characteristics.