LAMBERT, Lukas, Petr OUŘEDNÍČEK, Jan BRIZA, Walter GIEPMANS, Jiri JAHODA, Lukáš HRUŠKA and Jan DANES. Sub-milliSievert ultralow-dose CT colonography with iterative model reconstruction technique. PeerJ. London: PeerJ, 2016, vol. 2016, No 4, p. 1-15. ISSN 2167-8359. Available from: https://dx.doi.org/10.7717/peerj.1883.
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Basic information
Original name Sub-milliSievert ultralow-dose CT colonography with iterative model reconstruction technique
Authors LAMBERT, Lukas (203 Czech Republic), Petr OUŘEDNÍČEK (203 Czech Republic, belonging to the institution), Jan BRIZA (203 Czech Republic), Walter GIEPMANS (528 Netherlands), Jiri JAHODA (203 Czech Republic), Lukáš HRUŠKA (703 Slovakia, guarantor, belonging to the institution) and Jan DANES (203 Czech Republic).
Edition PeerJ, London, PeerJ, 2016, 2167-8359.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.177
RIV identification code RIV/00216224:14110/16:00090665
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.7717/peerj.1883
UT WoS 000374159800009
Keywords in English CT colonography; Polyp; Low-dose; Iterative reconstruction technique
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 30/8/2016 15:26.
Abstract
Purpose. The purpose of this study was to evaluate the technical and diagnostic performance of sub-milliSievert ultralow-dose (ULD) CT colonograpy (CTC) in the detection of colonic and extracolonic lesions. Materials and Methods. CTC with standard dose (SD) and ULD acquisitions of 64 matched patients, half of them with colonic findings, were reconstructed with filtered back projection (FBP), hybrid (HIR) and iterative model reconstruction techniques (IMR). Image noise in six colonic segments, in the left psoas muscle and aorta were measured. linage quality of the left adrenal gland and of the colon in the endoscopic and 2D view was rated on a five point Likert scale by two. observers, who also completed the reading of CTC for colonic and extracolonic findings. Results. The mean radiation dose estimate was 4.1 +/- 1.4 mSv for SD and 0.86 +/- 0.17 mSv for ULD for both positions (p < 0.0001). In ULD-IMR, SD-IMR and SD-HIR, the endoluminal noise was decreased in all colonic segments compared to SD FBP (P < 0.001) There were 27 small (6-9 mm) and 17 large (>= 10 mm) colonic lesions that were classified as sessile polyps (n = 38), flat lesions (n = 3), or as a mass (n = 3), Per patient sensitivity and specificity were 0.82 and 0.93 for ULD-FBP, 0.97 and 0.97p for ULD-HIR, 0.97 and 1.0 for ULD-IMR. Per polyp sensitivity was 0.84 for ULD-FBP, 0 98 ULD-HIR, 0.98 for ULD-IMR. Significantly less extracolonic findings were detected in ULD-FBP and ULD-HIR, but in the E4 category by C-BADS (potentially important findings), the detection was similar. Conclusion. Both HIR and IMR are suitable for sub-milliSievert ULD CTC with out sacrificing diagnostic performance of the study.
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