J 2016

Sub-milliSievert ultralow-dose CT colonography with iterative model reconstruction technique

LAMBERT, Lukas, Petr OUŘEDNÍČEK, Jan BRIZA, Walter GIEPMANS, Jiri JAHODA et. al.

Základní údaje

Originální název

Sub-milliSievert ultralow-dose CT colonography with iterative model reconstruction technique

Autoři

LAMBERT, Lukas (203 Česká republika), Petr OUŘEDNÍČEK (203 Česká republika, domácí), Jan BRIZA (203 Česká republika), Walter GIEPMANS (528 Nizozemské království), Jiri JAHODA (203 Česká republika), Lukáš HRUŠKA (703 Slovensko, garant, domácí) a Jan DANES (203 Česká republika)

Vydání

PeerJ, London, PeerJ, 2016, 2167-8359

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.177

Kód RIV

RIV/00216224:14110/16:00090665

Organizační jednotka

Lékařská fakulta

DOI

UT WoS

000374159800009

Klíčová slova anglicky

CT colonography; Polyp; Low-dose; Iterative reconstruction technique

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 30. 8. 2016 15:26, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Purpose. The purpose of this study was to evaluate the technical and diagnostic performance of sub-milliSievert ultralow-dose (ULD) CT colonograpy (CTC) in the detection of colonic and extracolonic lesions. Materials and Methods. CTC with standard dose (SD) and ULD acquisitions of 64 matched patients, half of them with colonic findings, were reconstructed with filtered back projection (FBP), hybrid (HIR) and iterative model reconstruction techniques (IMR). Image noise in six colonic segments, in the left psoas muscle and aorta were measured. linage quality of the left adrenal gland and of the colon in the endoscopic and 2D view was rated on a five point Likert scale by two. observers, who also completed the reading of CTC for colonic and extracolonic findings. Results. The mean radiation dose estimate was 4.1 +/- 1.4 mSv for SD and 0.86 +/- 0.17 mSv for ULD for both positions (p < 0.0001). In ULD-IMR, SD-IMR and SD-HIR, the endoluminal noise was decreased in all colonic segments compared to SD FBP (P < 0.001) There were 27 small (6-9 mm) and 17 large (>= 10 mm) colonic lesions that were classified as sessile polyps (n = 38), flat lesions (n = 3), or as a mass (n = 3), Per patient sensitivity and specificity were 0.82 and 0.93 for ULD-FBP, 0.97 and 0.97p for ULD-HIR, 0.97 and 1.0 for ULD-IMR. Per polyp sensitivity was 0.84 for ULD-FBP, 0 98 ULD-HIR, 0.98 for ULD-IMR. Significantly less extracolonic findings were detected in ULD-FBP and ULD-HIR, but in the E4 category by C-BADS (potentially important findings), the detection was similar. Conclusion. Both HIR and IMR are suitable for sub-milliSievert ULD CTC with out sacrificing diagnostic performance of the study.