Emergence of the First Catalytic Oligonucleotides in a
Formamide-Based Origin Scenario

J 2016

Emergence of the First Catalytic Oligonucleotides in a Formamide-Based Origin Scenario

ŠPONEROVÁ, Judit, Jiří ŠPONER, Olga NOVÁKOVÁ, Viktor BRABEC, Ondrej ŠEDO et. al.

Basic information

Original name

Emergence of the First Catalytic Oligonucleotides in a Formamide-Based Origin Scenario

Authors

ŠPONEROVÁ, Judit (348 Hungary, belonging to the institution), Jiří ŠPONER (203 Czech Republic, guarantor, belonging to the institution), Olga NOVÁKOVÁ (203 Czech Republic), Viktor BRABEC (203 Czech Republic), Ondrej ŠEDO (203 Czech Republic, belonging to the institution), Zbyněk ZDRÁHAL (203 Czech Republic, belonging to the institution), Giovanna COSTANZO (380 Italy), Samanta PINO (380 Italy), Raffaele SALADINO (380 Italy) and Ernesto DI MAURO (380 Italy)

Edition

Chemistry - A European Journal, WEINHEIM, Wiley, 2016, 0947-6539

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10403 Physical chemistry

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.317

RIV identification code

RIV/00216224:14740/16:00088109

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1002/chem.201503906

UT WoS

000371741400009

Keywords in English

formamide; nucleobases; nucleotides; origin of life; RNA

Abstract

V originále

50years after the historical Miller-Urey experiment, the formamide-based scenario is perhaps the most powerful concurrent hypothesis for the origin of life on our planet besides the traditional HCN-based concept. The information accumulated during the last 15years in this topic is astonishingly growing and nowadays the formamide-based model represents one of the most complete and coherent pathways leading from simple prebiotic precursors up to the first catalytically active RNA molecules. In this work, we overview the major events of this long pathway that have emerged from recent experimental and theoretical studies, mainly concentrating on the mechanistic, methodological, and structural aspects of this research.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

GBP206/12/G151, research and development project

Name: Centrum nových přístupů k bioanalýze a molekulární diagnostice

Citovat

ŠPONEROVÁ, Judit, Jiří ŠPONER, Olga NOVÁKOVÁ, Viktor BRABEC, Ondrej ŠEDO, Zbyněk ZDRÁHAL, Giovanna COSTANZO, Samanta PINO, Raffaele SALADINO and Ernesto DI MAURO. Emergence of the First Catalytic Oligonucleotides in a Formamide-Based Origin Scenario. Chemistry - A European Journal. WEINHEIM: Wiley, 2016, vol. 22, No 11, p. 3572-3586. ISSN 0947-6539. Available from: https://dx.doi.org/10.1002/chem.201503906.

@article{1352749,
   author = {Šponerová, Judit and Šponer, Jiří and Nováková, Olga and Brabec, Viktor and Šedo, Ondrej and Zdráhal, Zbyněk and Costanzo, Giovanna and Pino, Samanta and Saladino, Raffaele and Di Mauro, Ernesto},
   article_location = {WEINHEIM},
   article_number = {11},
   doi = {http://dx.doi.org/10.1002/chem.201503906},
   keywords = {formamide; nucleobases; nucleotides; origin of life; RNA},
   language = {eng},
   issn = {0947-6539},
   journal = {Chemistry - A European Journal},
   title = {Emergence of the First Catalytic Oligonucleotides in a Formamide-Based Origin Scenario},
   url = {http://onlinelibrary.wiley.com/doi/10.1002/chem.201503906/full},
   volume = {22},
   year = {2016}
}

TY  - JOUR
ID  - 1352749
AU  - Šponerová, Judit - Šponer, Jiří - Nováková, Olga - Brabec, Viktor - Šedo, Ondrej - Zdráhal, Zbyněk - Costanzo, Giovanna - Pino, Samanta - Saladino, Raffaele - Di Mauro, Ernesto
PY  - 2016
TI  - Emergence of the First Catalytic Oligonucleotides in a Formamide-Based Origin Scenario
JF  - Chemistry - A European Journal
VL  - 22
IS  - 11
SP  - 3572-3586
EP  - 3572-3586
PB  - Wiley
SN  - 09476539
KW  - formamide
KW  - nucleobases
KW  - nucleotides
KW  - origin of life
KW  - RNA
UR  - http://onlinelibrary.wiley.com/doi/10.1002/chem.201503906/full
L2  - http://onlinelibrary.wiley.com/doi/10.1002/chem.201503906/full
N2  - 50years after the historical Miller-Urey experiment, the formamide-based scenario is perhaps the most powerful concurrent hypothesis for the origin of life on our planet besides the traditional HCN-based concept. The information accumulated during the last 15years in this topic is astonishingly growing and nowadays the formamide-based model represents one of the most complete and coherent pathways leading from simple prebiotic precursors up to the first catalytically active RNA molecules. In this work, we overview the major events of this long pathway that have emerged from recent experimental and theoretical studies, mainly concentrating on the mechanistic, methodological, and structural aspects of this research.
ER  -

ŠPONEROVÁ, Judit, Jiří ŠPONER, Olga NOVÁKOVÁ, Viktor BRABEC, Ondrej ŠEDO, Zbyněk ZDRÁHAL, Giovanna COSTANZO, Samanta PINO, Raffaele SALADINO and Ernesto DI MAURO. Emergence of the First Catalytic Oligonucleotides in a Formamide-Based Origin Scenario. \textit{Chemistry - A European Journal}. WEINHEIM: Wiley, 2016, vol.~22, No~11, p.~3572-3586. ISSN~0947-6539. Available from: https://dx.doi.org/10.1002/chem.201503906.

Detailed Information on Publication Record