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@article{1353913, author = {Krejčí, Jan and Mlejnek, Dalibor and Sochorová, Dana and Němec, Petr}, article_location = {New York}, article_number = {4087632}, doi = {http://dx.doi.org/10.1155/2016/4087632}, keywords = {GIANT-CELL MYOCARDITIS; CARDIOVASCULAR MAGNETIC-RESONANCE; VENTRICULAR ENDOMYOCARDIAL BIOPSY; ACUTE VIRAL MYOCARDITIS; ONSET DILATED CARDIOMYOPATHY; HEART-FAILURE ASSOCIATION}, language = {eng}, issn = {2314-6133}, journal = {Biomed Research International}, title = {Inflammatory Cardiomyopathy: A Current View on the Pathophysiology, Diagnosis, and Treatment}, volume = {2016}, year = {2016} }
TY - JOUR ID - 1353913 AU - Krejčí, Jan - Mlejnek, Dalibor - Sochorová, Dana - Němec, Petr PY - 2016 TI - Inflammatory Cardiomyopathy: A Current View on the Pathophysiology, Diagnosis, and Treatment JF - Biomed Research International VL - 2016 IS - 4087632 SP - 1-11 EP - 1-11 PB - Hindawi Publishing Corporation SN - 23146133 KW - GIANT-CELL MYOCARDITIS KW - CARDIOVASCULAR MAGNETIC-RESONANCE KW - VENTRICULAR ENDOMYOCARDIAL BIOPSY KW - ACUTE VIRAL MYOCARDITIS KW - ONSET DILATED CARDIOMYOPATHY KW - HEART-FAILURE ASSOCIATION N2 - Inflammatory cardiomyopathy is defined as inflammation of the heart muscle associated with impaired function of the myocardium. In our region, its etiology is most often viral. Viral infection is a possible trigger of immune and autoimmune mechanisms which contributed to the damage of myocardial function. Myocarditis is considered the most common cause of dilated cardiomyopathy. Typical manifestation of this disease is heart failure, chest pain, or arrhythmias. The most important noninvasive diagnostic method is magnetic resonance imaging, but the gold standard of diagnostics is invasive examination, endomyocardial biopsy. In a significant proportion of cases with impaired left ventricular systolic function, recovery occurs spontaneously in several weeks and therefore it is appropriate to postpone critical therapeutic decisions about 3-6 months after start of the treatment. Therapy is based on standard heart failure treatment; immunosuppressive or antimicrobial treatment may be considered in some cases depending on the results of endomyocardial biopsy. If severe dysfunction of the left ventricle persists, device therapy may be needed. ER -
KREJČÍ, Jan, Dalibor MLEJNEK, Dana SOCHOROVÁ a Petr NĚMEC. Inflammatory Cardiomyopathy: A Current View on the Pathophysiology, Diagnosis, and Treatment. \textit{Biomed Research International}. New York: Hindawi Publishing Corporation, 2016, roč.~2016, č.~4087632, s.~1-11. ISSN~2314-6133. Dostupné z: https://dx.doi.org/10.1155/2016/4087632.
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