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@proceedings{1354568, author = {Skládal, Petr and Přibyl, Jan and Horáčková, Veronika and Pešl, Martin and Bouchal, Pavel and Gereg, Patrik and Jakubec, Martin and Farka, Zdeněk and Kovář, David}, booktitle = {SPM workshop 2015}, language = {eng}, title = {AFM for characterization of biomolecules, affinity complexes and cells}, url = {http://www.nanometrologie.cz/sbornik.pdf#page=5}, year = {2015} }
TY - CONF ID - 1354568 AU - Skládal, Petr - Přibyl, Jan - Horáčková, Veronika - Pešl, Martin - Bouchal, Pavel - Gereg, Patrik - Jakubec, Martin - Farka, Zdeněk - Kovář, David PY - 2015 TI - AFM for characterization of biomolecules, affinity complexes and cells UR - http://www.nanometrologie.cz/sbornik.pdf#page=5 N2 - The instrumentation and services available at the Core Facility of Nanobiotechnology, CEITEC Masaryk University, will be introduced. The research possibilities will be demonstrated on experiments with proteins, nucleic acids and their affinity complexes - interaction of ssDNA binding protein with oligonucleotides and immunoreaction between antibody and antigen. Properties of cellular membrane will be characterised in relation to the changes accompanying malignant transformation. Simultaneous recording of contractions and electric activity of cardiomyocytes will be presented using AFM cantilever with conductive tip functioning as nanomechanical transducer for cellular biosensor suitable for evaluation of fyziologically active compounds in real time. ER -
SKLÁDAL, Petr, Jan PŘIBYL, Veronika HORÁČKOVÁ, Martin PEŠL, Pavel BOUCHAL, Patrik GEREG, Martin JAKUBEC, Zdeněk FARKA a David KOVÁŘ. AFM for characterization of biomolecules, affinity complexes and cells. In \textit{SPM workshop 2015}. 2015.
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