Neuromodulation in Hypertension

NECHUTOVÁ, Hana, Miroslav SOUČEK, K. BRABENCOVA, R. STEPANOVA, Mojmír BLAHA a Jiří VANÍČEK. Neuromodulation in Hypertension. In 26th European Meeting on Hypertension and Cardiovascular Protection. 2016. ISSN 0263-6352.

Základní údaje

• Originální název: Neuromodulation in Hypertension
• Autoři: NECHUTOVÁ, Hana (203 Česká republika, garant, domácí), Miroslav SOUČEK (203 Česká republika, domácí), K. BRABENCOVA (203 Česká republika), R. STEPANOVA (203 Česká republika), Mojmír BLAHA (203 Česká republika, domácí) a Jiří VANÍČEK (203 Česká republika, domácí).
• Vydání: 26th European Meeting on Hypertension and Cardiovascular Protection, 2016.

Další údaje

• Originální jazyk: angličtina
• Typ výsledku: Konferenční abstrakt
• Obor: 30200 3.2 Clinical medicine
• Stát vydavatele: Spojené státy
• Utajení: není předmětem státního či obchodního tajemství
• Impakt faktor: Impact factor: 4.085
• Kód RIV: RIV/00216224:14110/16:00091178
• Organizační jednotka: Lékařská fakulta
• ISSN: 0263-6352
• Klíčová slova anglicky: brain neuron; Magnetic Resonance Imaging techniques
• Štítky: EL OK

Anotace

Objective: In our study, we focus on particular brain neurons and their axonal connections within the brainstem and spinal cord, which regulate the sympathetic and parasympathetic nerves functions, involved in the regulation of blood pressure. Processes of neuromodulation are mentioned to take place within these neural connections of central nervous system. The target group for analysis is represented by patients with hypertension. Design and method: We analysed the descending nervous fascicle in patients with hypertension and in healthy controls. All probands (16 patients with hypertension, 12 healthy controls) of our pilot study underwent the non-invasive, one-time magnetic resonance imaging scanning. For the central nervous system structures mapping, we have used the non-invasive Magnetic Resonance imaging techniques (3T MR system Discovery MR750 GE, software DV24.0_R01_1344.a), combined with specific software processing (Philips working station, MR Diffusion + MR FiberTrack analysis). Received data were analyzed by using statistics (Mann-Whitney test for comparison of parameters between groups). Results: For the oral presentation, the results are presented as very visual MRI - tractography images and clear Gauss curves comparisons too.