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@inproceedings{1357492,
author = {Stiborek, Marek and Nehybová, Tereza and Beneš, Petr and Kanický, Viktor and Preisler, Jan},
address = {Brno (ČR)},
booktitle = {CECE 2016 International Interdisciplinary Meeting on Bioanalysis},
keywords = {SALD-ICP-MS-wedelolactone-cancer-cell},
howpublished = {elektronická verze "online"},
language = {eng},
location = {Brno (ČR)},
isbn = {978-80-904959-4-4},
pages = {248-251},
publisher = {Neuveden},
title = {(SALD) ICP-MS to examine the effect of copper on wedelolactone cytotoxicity towards breast cancer cells},
year = {2016}
}
TY - JOUR
ID - 1357492
AU - Stiborek, Marek - Nehybová, Tereza - Beneš, Petr - Kanický, Viktor - Preisler, Jan
PY - 2016
TI - (SALD) ICP-MS to examine the effect of copper on wedelolactone cytotoxicity towards breast cancer cells
PB - Neuveden
CY - Brno (ČR)
SN - 9788090495944
KW - SALD-ICP-MS-wedelolactone-cancer-cell
N2 - In this study, the effect of copper on wedelolactone cytotoxicity towards breast cancer cells was examined. To monitor copper loading of cells, SALD ICP-MS (substrate assisted laser desorption inductively coupled plasma mass spectrometry) and conventional nebulizing ICP-MS analysis were used. The SALD technique provided direct and fast analysis of liquid samples in the form of dried droplets with minimal sample preparation and sub-microliter sample volume requirement. Furthermore, the SALD allowed direct analysis of samples in organic solvents, which could not be directly nebulised to ICP-MS. The experiments showed that copper chelation can drastically reduce wedelolactone cytotoxicity.
ER -
STIBOREK, Marek, Tereza NEHYBOVÁ, Petr BENEŠ, Viktor KANICKÝ a Jan PREISLER. (SALD) ICP-MS to examine the effect of copper on wedelolactone cytotoxicity towards breast cancer cells. Online. In \textit{CECE 2016 International Interdisciplinary Meeting on Bioanalysis}. Brno (ČR): Neuveden, 2016, s.~248-251. ISBN~978-80-904959-4-4.
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