Intestinal sulfate-reducing bacteria under the effect of
salicylamides derivatives

D 2016

Intestinal sulfate-reducing bacteria under the effect of salicylamides derivatives

KUSHKEVYCH, Ivan, Monika VÍTĚZOVÁ, Peter KOLLAR a Josef JAMPILEK

Základní údaje

Originální název

Intestinal sulfate-reducing bacteria under the effect of salicylamides derivatives

Autoři

KUSHKEVYCH, Ivan (804 Ukrajina, domácí), Monika VÍTĚZOVÁ (203 Česká republika, domácí), Peter KOLLAR (203 Česká republika) a Josef JAMPILEK (203 Česká republika)

Vydání

Ivan Franko Lviv National Un. Lviv, Achievements and prospects of microbiology, od s. 72-74, 3 s. 2016

Nakladatel

Ivan Franko Lviv National University

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Ukrajina

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Kód RIV

RIV/00216224:14310/16:00095905

Organizační jednotka

Přírodovědecká fakulta

ISBN

978-966-919-203-5

Klíčová slova anglicky

salicylamides; bowel diseases; ulcerative colitis; sulfate-reducing bacteria

Štítky

NZ, rivok

Změněno: 24. 3. 2018 20:09, Ing. Nicole Zrilić

Anotace

V originále

Sulfate-reducing bacteria (SRB) are most likely involved in both the initiation and maintenance of the inflammatory bowel disease (IBD), unfortunately present antibacterial chemotherapeutics used in the treatment of IBD have been ineffective. Thus, the antimicrobial activity of salicylamide derivatives on two different genera of intestinal SRB, Desulfovibrio and Desulfomicrobium was investigated. Six 2-(phenylcarbamoyl)phenyl N-[(benzyloxy)carbonyl]alkanoatesand three 2-hydroxy-N-[(2S)-1-oxo-1-(phenylamino)alkan-2-yl]benzamides showed MIC values in the range from 0.22 to 0.35 microM against Desulfovibrio piger Vib-7 and in the range from 0.27 to 8.52 microM against Desulfomicrobium sp. Rod-9, which is by two orders of magnitude lower compared with ciprofloxacin.

Citovat

KUSHKEVYCH, Ivan, Monika VÍTĚZOVÁ, Peter KOLLAR a Josef JAMPILEK. Intestinal sulfate-reducing bacteria under the effect of salicylamides derivatives. In Achievements and prospects of microbiology. Ivan Franko Lviv National Un. Lviv: Ivan Franko Lviv National University, 2016, s. 72-74. ISBN 978-966-919-203-5.

@inproceedings{1359523,
   author = {Kushkevych, Ivan and Vítězová, Monika and Kollar, Peter and Jampilek, Josef},
   address = {Lviv},
   booktitle = {Achievements and prospects of microbiology},
   edition = {Ivan Franko Lviv National Un},
   keywords = {salicylamides; bowel diseases; ulcerative colitis; sulfate-reducing bacteria},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Lviv},
   isbn = {978-966-919-203-5},
   pages = {72-74},
   publisher = {Ivan Franko Lviv National University},
   title = {Intestinal sulfate-reducing bacteria under the effect of salicylamides derivatives},
   year = {2016}
}

TY  - JOUR
ID  - 1359523
AU  - Kushkevych, Ivan - Vítězová, Monika - Kollar, Peter - Jampilek, Josef
PY  - 2016
TI  - Intestinal sulfate-reducing bacteria under the effect of salicylamides derivatives
PB  - Ivan Franko Lviv National University
CY  - Lviv
SN  - 9789669192035
KW  - salicylamides
KW  - bowel diseases
KW  - ulcerative colitis
KW  - sulfate-reducing bacteria
N2  - Sulfate-reducing bacteria (SRB) are most likely involved in both the initiation and maintenance of the inflammatory bowel disease (IBD), unfortunately present antibacterial chemotherapeutics used in the treatment of IBD have been ineffective. Thus, the antimicrobial activity of salicylamide derivatives on two different genera of intestinal SRB, Desulfovibrio and Desulfomicrobium was investigated. Six 2-(phenylcarbamoyl)phenyl N-[(benzyloxy)carbonyl]alkanoatesand three 2-hydroxy-N-[(2S)-1-oxo-1-(phenylamino)alkan-2-yl]benzamides showed MIC values in the range from 0.22 to 0.35 microM against Desulfovibrio piger Vib-7 and in the range from 0.27 to 8.52 microM against Desulfomicrobium sp. Rod-9, which is by two orders of magnitude lower compared with ciprofloxacin.
ER  -

KUSHKEVYCH, Ivan, Monika VÍTĚZOVÁ, Peter KOLLAR a Josef JAMPILEK. Intestinal sulfate-reducing bacteria under the effect of salicylamides derivatives. In \textit{Achievements and prospects of microbiology}. Ivan Franko Lviv National Un. Lviv: Ivan Franko Lviv National University, 2016, s.~72-74. ISBN~978-966-919-203-5.

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