KOMINKOVA, Marketa, Vedran MILOSAVLJEVIC, Petr VITEK, Hana POLANSKÁ, Kristyna CIHALOVA, Simona DOSTALOVA, Veronika HYNSTOVA, Roman GURÁŇ, Pavel KOPEL, Lukas RICHTERA, Michal MASAŘÍK, Martin BRTNICKY, Jindrich KYNICKY, Ondrej ZITKA a Vojtech ADAM. Comparative study on toxicity of extracellularly biosynthesized and laboratory synthesized CdTe quantum dots. Journal of Biotechnology. Amsterdam: Elsevier Science BV, 2017, roč. 241, "neuvedeno", s. 193-200. ISSN 0168-1656. Dostupné z: https://dx.doi.org/10.1016/j.jbiotec.2016.10.024. |
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@article{1361907, author = {Kominkova, Marketa and Milosavljevic, Vedran and Vitek, Petr and Polanská, Hana and Cihalova, Kristyna and Dostalova, Simona and Hynstova, Veronika and Guráň, Roman and Kopel, Pavel and Richtera, Lukas and Masařík, Michal and Brtnicky, Martin and Kynicky, Jindrich and Zitka, Ondrej and Adam, Vojtech}, article_location = {Amsterdam}, article_number = {"neuvedeno"}, doi = {http://dx.doi.org/10.1016/j.jbiotec.2016.10.024}, keywords = {Quantum dots; Biosynthesis; Escherichia coli (E. coli); CdTe; Toxicity}, language = {eng}, issn = {0168-1656}, journal = {Journal of Biotechnology}, title = {Comparative study on toxicity of extracellularly biosynthesized and laboratory synthesized CdTe quantum dots}, url = {http://dx.doi.org/10.1016/j.jbiotec.2016.10.024}, volume = {241}, year = {2017} }
TY - JOUR ID - 1361907 AU - Kominkova, Marketa - Milosavljevic, Vedran - Vitek, Petr - Polanská, Hana - Cihalova, Kristyna - Dostalova, Simona - Hynstova, Veronika - Guráň, Roman - Kopel, Pavel - Richtera, Lukas - Masařík, Michal - Brtnicky, Martin - Kynicky, Jindrich - Zitka, Ondrej - Adam, Vojtech PY - 2017 TI - Comparative study on toxicity of extracellularly biosynthesized and laboratory synthesized CdTe quantum dots JF - Journal of Biotechnology VL - 241 IS - "neuvedeno" SP - 193-200 EP - 193-200 PB - Elsevier Science BV SN - 01681656 KW - Quantum dots KW - Biosynthesis KW - Escherichia coli (E. coli) KW - CdTe KW - Toxicity UR - http://dx.doi.org/10.1016/j.jbiotec.2016.10.024 N2 - Nanobiosynthesis belongs to the most recent methods for synthesis of nanoparticles. This type of synthesis provides many advantages including the uniformity in particle shape and size. The biosynthesis has also a significant advantage regarding chemical properties of the obtained particles. In this study, we characterized the basic properties and composition of quantum dots (QDs), obtained by the extracellular biosynthesis by Escherichia coli. Furthermore, the toxicity of the biosynthesized QDs was compared to QDs prepared by microwave synthesis. The obtained results revealed the presence of cyan CdTe QDs after removal of substantial amounts of organic compounds, which stabilized the nanoparticle surface. QDs toxicity was evaluated using three cell lines Human Foreskin Fibroblast (HFF), Human Prostate Cancer cells (PC-3) and Breast Cancer cells (MCF-7) and the MTT assay. The test revealed differences in the toxicity between variants of QDs, varying about 10% in the HFF and 30% in the MCF-7 cell lines. The toxicity of the biosynthesized QDs to the PC-3 cell lines was about 35% lower in comparison with the QDs prepared by microwave synthesis. ER -
KOMINKOVA, Marketa, Vedran MILOSAVLJEVIC, Petr VITEK, Hana POLANSKÁ, Kristyna CIHALOVA, Simona DOSTALOVA, Veronika HYNSTOVA, Roman GURÁŇ, Pavel KOPEL, Lukas RICHTERA, Michal MASAŘÍK, Martin BRTNICKY, Jindrich KYNICKY, Ondrej ZITKA a Vojtech ADAM. Comparative study on toxicity of extracellularly biosynthesized and laboratory synthesized CdTe quantum dots. \textit{Journal of Biotechnology}. Amsterdam: Elsevier Science BV, 2017, roč.~241, ''neuvedeno'', s.~193-200. ISSN~0168-1656. Dostupné z: https://dx.doi.org/10.1016/j.jbiotec.2016.10.024.
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