| VOLEJNIKOVA, Jana, Viera BAJČIOVÁ, Lucie SULOVSKA, Marie GEIEROVA, Eva BURIANKOVA, Marie JAROSOVA, Marian HAJDUCH, Jaroslav ŠTĚRBA a Vladimir MIHAL. Bone marrow metastasis of malignant melanoma in childhood arising within a congenital melanocytic nevus. Biomedical Papers of the Faculty of Medicine of Palacký University. Olomouc: Palacký University, 2016, roč. 160, č. 3, s. 456-460. ISSN 1213-8118. Dostupné z: https://dx.doi.org/10.5507/bp.2016.018. |
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@article{1363076,
author = {Volejnikova, Jana and Bajčiová, Viera and Sulovska, Lucie and Geierova, Marie and Buriankova, Eva and Jarosova, Marie and Hajduch, Marian and Štěrba, Jaroslav and Mihal, Vladimir},
article_location = {Olomouc},
article_number = {3},
doi = {http://dx.doi.org/10.5507/bp.2016.018},
keywords = {Bone marrow; Childhood; Congenital melanocytic nevus; Malignant melanoma; Metastasis},
language = {cze},
issn = {1213-8118},
journal = {Biomedical Papers of the Faculty of Medicine of Palacký University},
title = {Bone marrow metastasis of malignant melanoma in childhood arising within a congenital melanocytic nevus},
volume = {160},
year = {2016}
}
TY - JOUR
ID - 1363076
AU - Volejnikova, Jana - Bajčiová, Viera - Sulovska, Lucie - Geierova, Marie - Buriankova, Eva - Jarosova, Marie - Hajduch, Marian - Štěrba, Jaroslav - Mihal, Vladimir
PY - 2016
TI - Bone marrow metastasis of malignant melanoma in childhood arising within a congenital melanocytic nevus
JF - Biomedical Papers of the Faculty of Medicine of Palacký University
VL - 160
IS - 3
SP - 456-460
EP - 456-460
PB - Palacký University
SN - 12138118
KW - Bone marrow
KW - Childhood
KW - Congenital melanocytic nevus
KW - Malignant melanoma
KW - Metastasis
N2 - Background. Malignant melanoma in childhood is infrequent and can arise within congenital melanocytic nevi. Spread of malignant melanoma to the bone marrow, especially in children, is extremely rare. Methods and Results. Reported is a case of a 5-year-old boy with a congenital large melanocytic nevus of the head and neck who presented with a short history of low back and leg pain, fever and cervical lymphadenopathy. Despite regular follow-up by a dermatologist and plastic surgeon and repeatedly negative histology of previous partial excisions, diffuse bone marrow infiltration with malignant melanoma was diagnosed. The primary site was identified in the post-excision area. The disease progressed rapidly on ipilimumab immunotherapy and led to death at four months from the diagnosis. Conclusion. Surveillance is indispensable in children with a predisposition to melanoma and nonspecific symptoms such as bone pain, gait impairment or cytopenia, should always be taken into account.
ER -
VOLEJNIKOVA, Jana, Viera BAJČIOVÁ, Lucie SULOVSKA, Marie GEIEROVA, Eva BURIANKOVA, Marie JAROSOVA, Marian HAJDUCH, Jaroslav ŠTĚRBA a Vladimir MIHAL. Bone marrow metastasis of malignant melanoma in childhood arising within a congenital melanocytic nevus. \textit{Biomedical Papers of the Faculty of Medicine of Palacký University}. Olomouc: Palacký University, 2016, roč.~160, č.~3, s.~456-460. ISSN~1213-8118. Dostupné z: https://dx.doi.org/10.5507/bp.2016.018.
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