GROSSOVÁ, Lucie, Radovan JIŘÍK, Eva DRAŽANOVÁ, Karel SOUČEK and Zenon STARČUK. Direct comparison of ASL and DCE-MRI in a mouse model of cancer. In Direct comparison of ASL and DCE-MRI in a mouse model of cancer. 2016. ISSN 1352-8661.
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Basic information
Original name Direct comparison of ASL and DCE-MRI in a mouse model of cancer
Authors GROSSOVÁ, Lucie, Radovan JIŘÍK, Eva DRAŽANOVÁ, Karel SOUČEK and Zenon STARČUK.
Edition Direct comparison of ASL and DCE-MRI in a mouse model of cancer, 2016.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30200 3.2 Clinical medicine
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.718
Organization unit Faculty of Medicine
ISSN 1352-8661
Keywords in English ASL DCE mouse MRI
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 26/4/2019 10:01.
Abstract
In recent years, several studies comparing ASL vs. DCE-MRI appeared due to an expansion of ASL from brain applications also to other organs (e.g. pulmonary parenchyma(1), tumour(2)). These studies indirectly compared blood flow (Fb) estimated with ASL to the perfusion parameters estimated by DCE-MRI which are only related to Fb but not equivalent. Our DCE-MRI method3 is based on the ATH pharmacokinetic model(4) providing estimates of Fb. This provides a direct comparison of the same quantity estimated using ASL and DCE-MRI. Compared to previous approaches aiming at replacement of one method by another, this study aims to prepare their combination and to provide more reliable perfusion-parameter estimate.
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