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@proceedings{1364968,
author = {Andrašina, Tomáš and Pánek, Jiří and Hlavsa, Jan and Bernard, Vladan and Válek, Vlastimil},
booktitle = {ESGAR 2016},
doi = {http://dx.doi.org/10.1007/s13244-016-0502-9},
keywords = {radiofrequency ablation; biliary cancer; percutaneous drainage},
language = {eng},
title = {Endoluminal radiofrequency ablation of hilarcholangiocarcinoma},
url = {http://paperity.org/p/76277811/esgar-2016-book-of-abstracts},
year = {2016}
}
TY - CONF
ID - 1364968
AU - Andrašina, Tomáš - Pánek, Jiří - Hlavsa, Jan - Bernard, Vladan - Válek, Vlastimil
PY - 2016
TI - Endoluminal radiofrequency ablation of hilarcholangiocarcinoma
KW - radiofrequency ablation
KW - biliary cancer
KW - percutaneous drainage
UR - http://paperity.org/p/76277811/esgar-2016-book-of-abstracts
L2 - http://paperity.org/p/76277811/esgar-2016-book-of-abstracts
N2 - Purpose: To prove efficacy of endoluminal radiofrequency ablation in palliative treatment of hilar cholangiocarcinoma. Material and methods: 35 patients with hilar cholangiocarcinoma have been enrolled in a prospective randomised study since 2010. The infiltrative type of cholangiocarcinoma was predominant. 65 non-covered self-expandable metal stents were inserted. In group A (n=18) the endoluminal ablation with a bipolar radiofrequency catheter (EndoHPB; EMcision Ltd., London, UK) was performed 0-48 hours prior to the stent insertion, in group B (n=17) the stent was implanted without a prior ablation. The primary endpoints of the study were to determine the rate of complications, duration of stent patency and survival of patients (Kaplan-Meier analysis). Results: The rate of biochemical pancreatitis, which was resolved in 3 days after stent insertion, was significantly higher in group A. The average primary stent patency was 5.9 and 5.7 months in groups A and B, respectively; 3-month and 6-month stent failure was 0% and 6.1% in group A and 6.3% and 25% in group B. The median survival from the initial drainage was 12.3 (6.7- 20.1) and 12.8 (5.7-14.7) months in groups A and B, respectively. Conclusion: The effect of an endoluminal ablation on patients survival was not proven in the prospective randomised clinical study. However, in the group of patients undergoing ablation there is a tendency of a lower rate of early stent failure. The intervention should be associated with very mild biochemical pancreatitis.
ER -
ANDRAŠINA, Tomáš, Jiří PÁNEK, Jan HLAVSA, Vladan BERNARD and Vlastimil VÁLEK. Endoluminal radiofrequency ablation of hilarcholangiocarcinoma. In \textit{ESGAR 2016}. 2016. Available from: https://dx.doi.org/10.1007/s13244-016-0502-9.
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