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@article{1365576, author = {Marcián, Václav and Filip, Pavel and Bareš, Martin and Brázdil, Milan}, article_location = {New York}, article_number = {6}, doi = {http://dx.doi.org/10.7916/D8KH0NBT}, keywords = {Ataxia; epilepsy; seizures; atrophy; stimulation}, language = {eng}, issn = {2160-8288}, journal = {Tremor and Other Hyperkinetic Movements}, title = {Cerebellar Dysfunction and Ataxia in Patients with Epilepsy: Coincidence, Consequence, or Cause?}, url = {https://www.ncbi.nlm.nih.gov/pubmed/27375960}, volume = {2016}, year = {2016} }
TY - JOUR ID - 1365576 AU - Marcián, Václav - Filip, Pavel - Bareš, Martin - Brázdil, Milan PY - 2016 TI - Cerebellar Dysfunction and Ataxia in Patients with Epilepsy: Coincidence, Consequence, or Cause? JF - Tremor and Other Hyperkinetic Movements VL - 2016 IS - 6 SP - 1-12 EP - 1-12 PB - The Center for Digital Research and Scholarship, Columbia University Libraries / Information Services SN - 21608288 KW - Ataxia KW - epilepsy KW - seizures KW - atrophy KW - stimulation UR - https://www.ncbi.nlm.nih.gov/pubmed/27375960 L2 - https://www.ncbi.nlm.nih.gov/pubmed/27375960 N2 - Basic epilepsy teachings assert that seizures arise from the cerebral cortex, glossing over infratentorial structures such as the cerebellum that are believed to modulate rather than generate seizures. Nonetheless, ataxia and other clinical findings in epileptic patients are slowly but inevitably drawing attention to this neural node. Tracing the evolution of this line of inquiry from the observed coincidence of cerebellar atrophy and cerebellar dysfunction (most apparently manifested as ataxia) in epilepsy to their close association, this review considers converging clinical, physiological, histological, and neuroimaging evidence that support incorporating the cerebellum into epilepsy pathology. We examine reports of still controversial cerebellar epilepsy, studies of cerebellar stimulation alleviating paroxysmal epileptic activity, studies and case reports of cerebellar lesions directly associated with seizures, and conditions in which ataxia is accompanied by epileptic seizures. Finally, the review substantiates the role of this complex brain structure in epilepsy whether by coincidence, as a consequence of deleterious cortical epileptic activity or antiepileptic drugs, or the very cause of the disease. ER -
MARCIÁN, Václav, Pavel FILIP, Martin BAREŠ and Milan BRÁZDIL. Cerebellar Dysfunction and Ataxia in Patients with Epilepsy: Coincidence, Consequence, or Cause? \textit{Tremor and Other Hyperkinetic Movements}. New York: The Center for Digital Research and Scholarship, Columbia University Libraries / Information Services, 2016, vol.~2016, No~6, p.~1-12. ISSN~2160-8288. Available from: https://dx.doi.org/10.7916/D8KH0NBT.
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