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@article{1365576,
author = {Marcián, Václav and Filip, Pavel and Bareš, Martin and Brázdil, Milan},
article_location = {New York},
article_number = {6},
doi = {http://dx.doi.org/10.7916/D8KH0NBT},
keywords = {Ataxia; epilepsy; seizures; atrophy; stimulation},
language = {eng},
issn = {2160-8288},
journal = {Tremor and Other Hyperkinetic Movements},
title = {Cerebellar Dysfunction and Ataxia in Patients with Epilepsy: Coincidence, Consequence, or Cause?},
url = {https://www.ncbi.nlm.nih.gov/pubmed/27375960},
volume = {2016},
year = {2016}
}
TY - JOUR
ID - 1365576
AU - Marcián, Václav - Filip, Pavel - Bareš, Martin - Brázdil, Milan
PY - 2016
TI - Cerebellar Dysfunction and Ataxia in Patients with Epilepsy: Coincidence, Consequence, or Cause?
JF - Tremor and Other Hyperkinetic Movements
VL - 2016
IS - 6
SP - 1-12
EP - 1-12
PB - The Center for Digital Research and Scholarship, Columbia University Libraries / Information Services
SN - 21608288
KW - Ataxia
KW - epilepsy
KW - seizures
KW - atrophy
KW - stimulation
UR - https://www.ncbi.nlm.nih.gov/pubmed/27375960
L2 - https://www.ncbi.nlm.nih.gov/pubmed/27375960
N2 - Basic epilepsy teachings assert that seizures arise from the cerebral cortex, glossing over infratentorial structures such as the cerebellum that are believed to modulate rather than generate seizures. Nonetheless, ataxia and other clinical findings in epileptic patients are slowly but inevitably drawing attention to this neural node. Tracing the evolution of this line of inquiry from the observed coincidence of cerebellar atrophy and cerebellar dysfunction (most apparently manifested as ataxia) in epilepsy to their close association, this review considers converging clinical, physiological, histological, and neuroimaging evidence that support incorporating the cerebellum into epilepsy pathology. We examine reports of still controversial cerebellar epilepsy, studies of cerebellar stimulation alleviating paroxysmal epileptic activity, studies and case reports of cerebellar lesions directly associated with seizures, and conditions in which ataxia is accompanied by epileptic seizures. Finally, the review substantiates the role of this complex brain structure in epilepsy whether by coincidence, as a consequence of deleterious cortical epileptic activity or antiepileptic drugs, or the very cause of the disease.
ER -
MARCIÁN, Václav, Pavel FILIP, Martin BAREŠ a Milan BRÁZDIL. Cerebellar Dysfunction and Ataxia in Patients with Epilepsy: Coincidence, Consequence, or Cause? \textit{Tremor and Other Hyperkinetic Movements}. New York: The Center for Digital Research and Scholarship, Columbia University Libraries / Information Services, 2016, roč.~2016, č.~6, s.~1-12. ISSN~2160-8288. Dostupné z: https://dx.doi.org/10.7916/D8KH0NBT.
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