Další formáty:
BibTeX
LaTeX
RIS
@article{1367310, author = {Indráková, Adéla and Mašlaňová, Ivana and Kováčová, Viera and Doškař, Jiří and Pantůček, Roman}, article_number = {11}, doi = {http://dx.doi.org/10.1515/biolog-2016-0156}, keywords = {Staphylococcus; methicillin-resistant Staphylococcus aureus (MRSA); staphylococcal cassette chromosome; evolution; mobile genetic elements}, language = {eng}, issn = {0006-3088}, journal = {Biologia}, title = {The evolutionary pathway of the staphylococcal cassette chromosome element}, url = {https://www.degruyter.com/view/j/biolog.2016.71.issue-11/biolog-2016-0156/biolog-2016-0156.xml}, volume = {71}, year = {2016} }
TY - JOUR ID - 1367310 AU - Indráková, Adéla - Mašlaňová, Ivana - Kováčová, Viera - Doškař, Jiří - Pantůček, Roman PY - 2016 TI - The evolutionary pathway of the staphylococcal cassette chromosome element JF - Biologia VL - 71 IS - 11 SP - 1195-1203 EP - 1195-1203 PB - Springer SN - 00063088 KW - Staphylococcus KW - methicillin-resistant Staphylococcus aureus (MRSA) KW - staphylococcal cassette chromosome KW - evolution KW - mobile genetic elements UR - https://www.degruyter.com/view/j/biolog.2016.71.issue-11/biolog-2016-0156/biolog-2016-0156.xml L2 - https://www.degruyter.com/view/j/biolog.2016.71.issue-11/biolog-2016-0156/biolog-2016-0156.xml N2 - The staphylococcal cassette chromosome (SCC) element can carry resistance genes to antibiotics, disinfectants, and heavy metals, contributing to the survival of strains in the environment and causing difficulties in the treatment of staphylococcal infections. Methicillin resistance in staphylococci, which is of particular clinical significance, is encoded by staphylococcal cassette chromosome mec (SCCmec). Despite the importance of the SCC element and description of multiple nucleotide sequences, the information about its origin and evolution is still scarce. Here, we present a phylogenetic analysis of SCC elements that is unique in the use of whole SCC sequences. A phylogenetic tree for a noteworthy number of 81 SCC elements based on global sequence alignment was constructed. The SCC clustering did not reflect the genetic relationships of bacteria containing the SCC elements, but was done according to type, determined by the combination of mec gene complex class and ccr gene complex type. The results emphasise the horizontal gene transfer as a means of spread of SCC elements in bacterial strains. Overall, this study contributes to the understanding of SCC emergence, evolution, and dissemination. ER -
INDRÁKOVÁ, Adéla, Ivana MAŠLAŇOVÁ, Viera KOVÁČOVÁ, Jiří DOŠKAŘ a Roman PANTŮČEK. The evolutionary pathway of the staphylococcal cassette chromosome element. \textit{Biologia}. Springer, 2016, roč.~71, č.~11, s.~1195-1203. ISSN~0006-3088. Dostupné z: https://dx.doi.org/10.1515/biolog-2016-0156.
|