Qualitative Evaluation of the Composition of Refluxate by
24-hour Multichannel Esophageal Intraluminal Impedance and
Ph-monitoring and its Relationship with Extraesophageal Reflux
Disease

a 2016

Qualitative Evaluation of the Composition of Refluxate by 24-hour Multichannel Esophageal Intraluminal Impedance and Ph-monitoring and its Relationship with Extraesophageal Reflux Disease

KONEČNÝ, Štefan, Radek KROUPA, Tomáš PAVLÍK a Jiří DOLINA

Základní údaje

Originální název

Qualitative Evaluation of the Composition of Refluxate by 24-hour Multichannel Esophageal Intraluminal Impedance and Ph-monitoring and its Relationship with Extraesophageal Reflux Disease

Autoři

KONEČNÝ, Štefan (703 Slovensko, domácí), Radek KROUPA (203 Česká republika, domácí), Tomáš PAVLÍK (203 Česká republika, domácí) a Jiří DOLINA (203 Česká republika, domácí)

Vydání

UEG (United European Gastroenterology) Week 2016, Vienna, 2016

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Rakousko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.673

Kód RIV

RIV/00216224:14110/16:00093230

Organizační jednotka

Lékařská fakulta

ISSN

DOI

http://dx.doi.org/10.1177/2050640616663689

Klíčová slova česky

reflux; refluxní nemoc jícnu; GERD; extraezofageální příznaky

Klíčová slova anglicky

reflux; gastroesophageal reflux disease; GERD; extraesophageal symptoms

Štítky

EL OK

Změněno: 14. 2. 2017 12:18, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

We presented a study focused on qualitative evaluation of the composition of refluxate and its relationship with extraesophageal symptoms. Gastroesophageal reflux disease (GERD) is a disease caused by backflow of gastric contents into the esophagus due to the failure of physiological antireflux mechanisms and can lead to esophageal and extraesophageal symptomatology. Extraesophageal reflux (EER) is a condition where refluxate penetrate above the upper esophageal sphincter (UES) in to the oral cavity, pharynx, upper and lower respiratory tract and leads to pathological changes. The examinations in our study were carried out using 24-hour multichannel intraluminal impedance and pH esophageal monitoring (MII-pH), which compared to the more commonly used conventional pH-monitoring can accurately detect reflux episodes at all pH levels and divide the episodes to acid reflux, weakly acidic reflux and nonacid reflux, and also provides information of the composition of refluxate (liquid, gas and mixture). We evaluated results of the examinations from 200 patients in two groups. The first group included 100 patients with classic GERD and in the second group were 100 patients with EER symptoms. We evaluated DeMeester score, the number of reflux episodes by pH, simultaneously the state of matter and the rate of penetration in the UES area. Patients with EER symptoms have more weakly acid reflux episodes and fewer acid reflux episodes compared to a group of patients with classical GERD symptoms while we found minor differences in the frequency of individual components of refluxate. In the group with EER we also observed lower values of DeMeester score, a higher number of gaseous reflux episodes and generally significantly higher number of penetration of refluxate of all states of matter to the UES area.

Citovat

KONEČNÝ, Štefan, Radek KROUPA, Tomáš PAVLÍK a Jiří DOLINA. Qualitative Evaluation of the Composition of Refluxate by 24-hour Multichannel Esophageal Intraluminal Impedance and Ph-monitoring and its Relationship with Extraesophageal Reflux Disease. In UEG (United European Gastroenterology) Week 2016, Vienna. 2016. ISSN 2050-6406. Dostupné z: https://dx.doi.org/10.1177/2050640616663689.

@proceedings{1370231,
   author = {Konečný, Štefan and Kroupa, Radek and Pavlík, Tomáš and Dolina, Jiří},
   booktitle = {UEG (United European Gastroenterology) Week 2016, Vienna},
   doi = {http://dx.doi.org/10.1177/2050640616663689},
   keywords = {reflux; gastroesophageal reflux disease; GERD; extraesophageal symptoms},
   language = {eng},
   title = {Qualitative Evaluation of the Composition of Refluxate by 24-hour Multichannel Esophageal Intraluminal Impedance and Ph-monitoring and its Relationship with Extraesophageal Reflux Disease},
   url = {http://journals.sagepub.com/doi/pdf/10.1177/2050640616663689},
   year = {2016}
}

TY  - CONF
ID  - 1370231
AU  - Konečný, Štefan - Kroupa, Radek - Pavlík, Tomáš - Dolina, Jiří
PY  - 2016
TI  - Qualitative Evaluation of the Composition of Refluxate by 24-hour Multichannel Esophageal Intraluminal Impedance and Ph-monitoring and its Relationship with Extraesophageal Reflux Disease
KW  - reflux
KW  - gastroesophageal reflux disease
KW  - GERD
KW  - extraesophageal symptoms
UR  - http://journals.sagepub.com/doi/pdf/10.1177/2050640616663689
N2  - We presented a study focused on qualitative evaluation of the composition of refluxate and its relationship with extraesophageal symptoms. Gastroesophageal reflux disease (GERD) is a disease caused by backflow of gastric contents into the esophagus due to the failure of physiological antireflux mechanisms and can lead to esophageal and extraesophageal symptomatology. Extraesophageal reflux (EER) is a condition where refluxate penetrate above the upper esophageal sphincter (UES) in to the oral cavity, pharynx, upper and lower respiratory tract and leads to pathological changes. The examinations in our study were carried out using 24-hour multichannel intraluminal impedance and pH esophageal monitoring (MII-pH), which compared to the more commonly used conventional pH-monitoring can accurately detect reflux episodes at all pH levels and divide the episodes to acid reflux, weakly acidic reflux and nonacid reflux, and also provides information of the composition of refluxate (liquid, gas and mixture). We evaluated results of the examinations from 200 patients in two groups. The first group included 100 patients with classic GERD and in the second group were 100 patients with EER symptoms. We evaluated DeMeester score, the number of reflux episodes by pH, simultaneously the state of matter and the rate of penetration in the UES area. Patients with EER symptoms have more weakly acid reflux episodes and fewer acid reflux episodes compared to a group of patients with classical GERD symptoms while we found minor differences in the frequency of individual components of refluxate. In the group with EER we also observed lower values of DeMeester score, a higher number of gaseous reflux episodes and generally significantly higher number of penetration of refluxate of all states of matter to the UES area.
ER  -

KONEČNÝ, Štefan, Radek KROUPA, Tomáš PAVLÍK a Jiří DOLINA. Qualitative Evaluation of the Composition of Refluxate by 24-hour Multichannel Esophageal Intraluminal Impedance and Ph-monitoring and its Relationship with Extraesophageal Reflux Disease. In \textit{UEG (United European Gastroenterology) Week 2016, Vienna}. 2016. ISSN~2050-6406. Dostupné z: https://dx.doi.org/10.1177/2050640616663689.

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